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Surgical Management in a Paediatric Case of Endobronchial Mucoepidermoid Carcinoma Involving the Carina

Although mucoepidermoid carcinoma (MEC) is the most diagnosed malignancy of the salivary gland, it rarely localises to the bronchus, accounting for only 0.1-0.2% of all primary lung malignancies. Of those pulmonary MECs, most are found in segmental or lobar bronchi, and they are rarely found in main...

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Autores principales: Boyle, Mark A, Rotimi, Oloruntobi, Palmares, Abigail, Alvarez Gallesio, Jose, Alshammari, Abdullah, Semple, Thomas, Buderi, Silviu, Jordan, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642615/
https://www.ncbi.nlm.nih.gov/pubmed/37965236
http://dx.doi.org/10.7759/cureus.48680
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author Boyle, Mark A
Rotimi, Oloruntobi
Palmares, Abigail
Alvarez Gallesio, Jose
Alshammari, Abdullah
Semple, Thomas
Buderi, Silviu
Jordan, Simon
author_facet Boyle, Mark A
Rotimi, Oloruntobi
Palmares, Abigail
Alvarez Gallesio, Jose
Alshammari, Abdullah
Semple, Thomas
Buderi, Silviu
Jordan, Simon
author_sort Boyle, Mark A
collection PubMed
description Although mucoepidermoid carcinoma (MEC) is the most diagnosed malignancy of the salivary gland, it rarely localises to the bronchus, accounting for only 0.1-0.2% of all primary lung malignancies. Of those pulmonary MECs, most are found in segmental or lobar bronchi, and they are rarely found in mainstem bronchi, highlighting the novelty of this presentation for thoracic specialists. We present a case report of a seven-year-old female who underwent a carinal resection and a right upper lobectomy for the management of an endobronchial MEC causing right middle lobe (RML) obstruction. Intraoperatively, an exophytic mass originating from the junction of the right main bronchus and bronchus intermedius was identified, causing a partial obstruction of the RML bronchus. Frozen sections demonstrated clear margins and follow-up bronchoscopies have been unremarkable. Given their rarity, endobronchial MECs can be diagnostically difficult and cause uncertainty with respect to their management. Low-grade tumours have a much more favourable prognosis than their high-grade counterparts, with surgical resection being the gold standard of care. Therefore, the index of suspicion, time to diagnosis, and definitive treatment are critical to the outcome.
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spelling pubmed-106426152023-11-14 Surgical Management in a Paediatric Case of Endobronchial Mucoepidermoid Carcinoma Involving the Carina Boyle, Mark A Rotimi, Oloruntobi Palmares, Abigail Alvarez Gallesio, Jose Alshammari, Abdullah Semple, Thomas Buderi, Silviu Jordan, Simon Cureus Pediatric Surgery Although mucoepidermoid carcinoma (MEC) is the most diagnosed malignancy of the salivary gland, it rarely localises to the bronchus, accounting for only 0.1-0.2% of all primary lung malignancies. Of those pulmonary MECs, most are found in segmental or lobar bronchi, and they are rarely found in mainstem bronchi, highlighting the novelty of this presentation for thoracic specialists. We present a case report of a seven-year-old female who underwent a carinal resection and a right upper lobectomy for the management of an endobronchial MEC causing right middle lobe (RML) obstruction. Intraoperatively, an exophytic mass originating from the junction of the right main bronchus and bronchus intermedius was identified, causing a partial obstruction of the RML bronchus. Frozen sections demonstrated clear margins and follow-up bronchoscopies have been unremarkable. Given their rarity, endobronchial MECs can be diagnostically difficult and cause uncertainty with respect to their management. Low-grade tumours have a much more favourable prognosis than their high-grade counterparts, with surgical resection being the gold standard of care. Therefore, the index of suspicion, time to diagnosis, and definitive treatment are critical to the outcome. Cureus 2023-11-12 /pmc/articles/PMC10642615/ /pubmed/37965236 http://dx.doi.org/10.7759/cureus.48680 Text en Copyright © 2023, Boyle et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pediatric Surgery
Boyle, Mark A
Rotimi, Oloruntobi
Palmares, Abigail
Alvarez Gallesio, Jose
Alshammari, Abdullah
Semple, Thomas
Buderi, Silviu
Jordan, Simon
Surgical Management in a Paediatric Case of Endobronchial Mucoepidermoid Carcinoma Involving the Carina
title Surgical Management in a Paediatric Case of Endobronchial Mucoepidermoid Carcinoma Involving the Carina
title_full Surgical Management in a Paediatric Case of Endobronchial Mucoepidermoid Carcinoma Involving the Carina
title_fullStr Surgical Management in a Paediatric Case of Endobronchial Mucoepidermoid Carcinoma Involving the Carina
title_full_unstemmed Surgical Management in a Paediatric Case of Endobronchial Mucoepidermoid Carcinoma Involving the Carina
title_short Surgical Management in a Paediatric Case of Endobronchial Mucoepidermoid Carcinoma Involving the Carina
title_sort surgical management in a paediatric case of endobronchial mucoepidermoid carcinoma involving the carina
topic Pediatric Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642615/
https://www.ncbi.nlm.nih.gov/pubmed/37965236
http://dx.doi.org/10.7759/cureus.48680
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