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Surgical Management in a Paediatric Case of Endobronchial Mucoepidermoid Carcinoma Involving the Carina
Although mucoepidermoid carcinoma (MEC) is the most diagnosed malignancy of the salivary gland, it rarely localises to the bronchus, accounting for only 0.1-0.2% of all primary lung malignancies. Of those pulmonary MECs, most are found in segmental or lobar bronchi, and they are rarely found in main...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642615/ https://www.ncbi.nlm.nih.gov/pubmed/37965236 http://dx.doi.org/10.7759/cureus.48680 |
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author | Boyle, Mark A Rotimi, Oloruntobi Palmares, Abigail Alvarez Gallesio, Jose Alshammari, Abdullah Semple, Thomas Buderi, Silviu Jordan, Simon |
author_facet | Boyle, Mark A Rotimi, Oloruntobi Palmares, Abigail Alvarez Gallesio, Jose Alshammari, Abdullah Semple, Thomas Buderi, Silviu Jordan, Simon |
author_sort | Boyle, Mark A |
collection | PubMed |
description | Although mucoepidermoid carcinoma (MEC) is the most diagnosed malignancy of the salivary gland, it rarely localises to the bronchus, accounting for only 0.1-0.2% of all primary lung malignancies. Of those pulmonary MECs, most are found in segmental or lobar bronchi, and they are rarely found in mainstem bronchi, highlighting the novelty of this presentation for thoracic specialists. We present a case report of a seven-year-old female who underwent a carinal resection and a right upper lobectomy for the management of an endobronchial MEC causing right middle lobe (RML) obstruction. Intraoperatively, an exophytic mass originating from the junction of the right main bronchus and bronchus intermedius was identified, causing a partial obstruction of the RML bronchus. Frozen sections demonstrated clear margins and follow-up bronchoscopies have been unremarkable. Given their rarity, endobronchial MECs can be diagnostically difficult and cause uncertainty with respect to their management. Low-grade tumours have a much more favourable prognosis than their high-grade counterparts, with surgical resection being the gold standard of care. Therefore, the index of suspicion, time to diagnosis, and definitive treatment are critical to the outcome. |
format | Online Article Text |
id | pubmed-10642615 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-106426152023-11-14 Surgical Management in a Paediatric Case of Endobronchial Mucoepidermoid Carcinoma Involving the Carina Boyle, Mark A Rotimi, Oloruntobi Palmares, Abigail Alvarez Gallesio, Jose Alshammari, Abdullah Semple, Thomas Buderi, Silviu Jordan, Simon Cureus Pediatric Surgery Although mucoepidermoid carcinoma (MEC) is the most diagnosed malignancy of the salivary gland, it rarely localises to the bronchus, accounting for only 0.1-0.2% of all primary lung malignancies. Of those pulmonary MECs, most are found in segmental or lobar bronchi, and they are rarely found in mainstem bronchi, highlighting the novelty of this presentation for thoracic specialists. We present a case report of a seven-year-old female who underwent a carinal resection and a right upper lobectomy for the management of an endobronchial MEC causing right middle lobe (RML) obstruction. Intraoperatively, an exophytic mass originating from the junction of the right main bronchus and bronchus intermedius was identified, causing a partial obstruction of the RML bronchus. Frozen sections demonstrated clear margins and follow-up bronchoscopies have been unremarkable. Given their rarity, endobronchial MECs can be diagnostically difficult and cause uncertainty with respect to their management. Low-grade tumours have a much more favourable prognosis than their high-grade counterparts, with surgical resection being the gold standard of care. Therefore, the index of suspicion, time to diagnosis, and definitive treatment are critical to the outcome. Cureus 2023-11-12 /pmc/articles/PMC10642615/ /pubmed/37965236 http://dx.doi.org/10.7759/cureus.48680 Text en Copyright © 2023, Boyle et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Pediatric Surgery Boyle, Mark A Rotimi, Oloruntobi Palmares, Abigail Alvarez Gallesio, Jose Alshammari, Abdullah Semple, Thomas Buderi, Silviu Jordan, Simon Surgical Management in a Paediatric Case of Endobronchial Mucoepidermoid Carcinoma Involving the Carina |
title | Surgical Management in a Paediatric Case of Endobronchial Mucoepidermoid Carcinoma Involving the Carina |
title_full | Surgical Management in a Paediatric Case of Endobronchial Mucoepidermoid Carcinoma Involving the Carina |
title_fullStr | Surgical Management in a Paediatric Case of Endobronchial Mucoepidermoid Carcinoma Involving the Carina |
title_full_unstemmed | Surgical Management in a Paediatric Case of Endobronchial Mucoepidermoid Carcinoma Involving the Carina |
title_short | Surgical Management in a Paediatric Case of Endobronchial Mucoepidermoid Carcinoma Involving the Carina |
title_sort | surgical management in a paediatric case of endobronchial mucoepidermoid carcinoma involving the carina |
topic | Pediatric Surgery |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642615/ https://www.ncbi.nlm.nih.gov/pubmed/37965236 http://dx.doi.org/10.7759/cureus.48680 |
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