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DNA supercoiling in bacteria: state of play and challenges from a viewpoint of physics based modeling

DNA supercoiling is central to many fundamental processes of living organisms. Its average level along the chromosome and over time reflects the dynamic equilibrium of opposite activities of topoisomerases, which are required to relax mechanical stresses that are inevitably produced during DNA repli...

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Detalles Bibliográficos
Autores principales: Junier, Ivan, Ghobadpour, Elham, Espeli, Olivier, Everaers, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642903/
https://www.ncbi.nlm.nih.gov/pubmed/37965550
http://dx.doi.org/10.3389/fmicb.2023.1192831