Cargando…

Obstructive nephropathy and molecular pathophysiology of renal interstitial fibrosis

The kidneys play a key role in maintaining total body homeostasis. The complexity of this task is reflected in the unique architecture of the organ. Ureteral obstruction greatly affects renal physiology by altering hemodynamics, changing glomerular filtration and renal metabolism, and inducing archi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nørregaard, Rikke, Mutsaers, Henricus A. M., Frøkiær, Jørgen, Kwon, Tae-Hwan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Physiological Society 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642920/ https://www.ncbi.nlm.nih.gov/pubmed/37440209 http://dx.doi.org/10.1152/physrev.00027.2022

Ejemplares similares

Physiology and pathophysiology of cyclooxygenase-2 and prostaglandin E2 in the kidney
por: Nørregaard, Rikke, et al.
Publicado: (2015)

Prostaglandin E2 receptors as therapeutic targets in renal fibrosis
por: Mutsaers, Henricus A.M., et al.
Publicado: (2022)

Transcutaneous measurement of renal function in two rodent models of obstructive nephropathy
por: Jensen, Michael Schou, et al.
Publicado: (2023)

Activation of the prostaglandin E(2) EP(2) receptor attenuates renal fibrosis in unilateral ureteral obstructed mice and human kidney slices
por: Jensen, Michael Schou, et al.
Publicado: (2019)

Editorial: Organ Fibrosis: Pathogenesis, Biomarkers and Therapeutic Targets
por: Mutsaers, Henricus A. M., et al.
Publicado: (2021)

Phenformin Attenuates Renal Injury in Unilateral Ureteral Obstructed Mice without Affecting Immune Cell Infiltration
por: Nørgård, Mikkel Ø., et al.
Publicado: (2020)

Research progress on the mechanism of renal interstitial fibrosis in obstructive nephropathy
por: Wang, Kangning, et al.
Publicado: (2023)

Local Inhibition of Indoleamine 2,3-Dioxygenase Mitigates Renal Fibrosis
por: Jensen, Camilla Grønkjær, et al.
Publicado: (2021)

Tamoxifen Decreases Lithium-Induced Natriuresis in Rats With Nephrogenic Diabetes Insipidus
por: Tingskov, Stine Julie, et al.
Publicado: (2018)

EP(1) receptor antagonism mitigates early and late stage renal fibrosis
por: Kresse, Jean‐Claude, et al.
Publicado: (2022)

A novel strategy employing the flavonoid fisetin to halt the progression of renal fibrosis in obstructive nephropathy
por: Kwon, Tae-Hwan
Publicado: (2023)

The impact of fibrotic diseases on global mortality from 1990 to 2019
por: Mutsaers, Henricus A. M., et al.
Publicado: (2023)

Regulation of aquaporin-2 in the kidney: A molecular mechanism of body-water homeostasis
por: Kwon, Tae-Hwan, et al.
Publicado: (2013)

Development of intestinal ischemia/reperfusion-induced acute kidney injury in rats with or without chronic kidney disease: Cytokine/chemokine response and effect of α-melanocyte-stimulating hormone
por: Skott, Martin, et al.
Publicado: (2014)

Chitosan/siRNA Nanoparticles Targeting Cyclooxygenase Type 2 Attenuate Unilateral Ureteral Obstruction-induced Kidney Injury in Mice
por: Yang, Chuanxu, et al.
Publicado: (2015)

Adenosine A(2A) Receptor: A Target for Regulating Renal Interstitial Fibrosis in Obstructive Nephropathy
por: Xiao, Hang, et al.
Publicado: (2013)

Protease‐activated receptor‐1 contributes to renal injury and interstitial fibrosis during chronic obstructive nephropathy
por: Waasdorp, Maaike, et al.
Publicado: (2018)

Reduced NOV/CCN3 Expression Limits Inflammation and Interstitial Renal Fibrosis after Obstructive Nephropathy in Mice
por: Marchal, Pierre-Olivier, et al.
Publicado: (2015)

Hydrogen sulfide inhibits the renal fibrosis of obstructive nephropathy
por: Song, Kai, et al.
Publicado: (2014)

SKLB023 hinders renal interstitial fibrosis in obstructive nephropathy by interfering TGF-β1/Smad3 signaling
por: Feng, Yanhuan, et al.
Publicado: (2018)

Role of inflammation in túbulo-interstitial damage associated to obstructive nephropathy
por: Grande, María T, et al.
Publicado: (2010)

Uromodulin deficiency alters tubular injury and interstitial inflammation but not fibrosis in experimental obstructive nephropathy
por: Maydan, Olena, et al.
Publicado: (2018)

Age-related changes in expression in renal AQPs in response to congenital, partial, unilateral ureteral obstruction in rats
por: Wang, Guixian, et al.
Publicado: (2011)

Editorial: Organ Fibrosis: Triggers, Pathways, and Cellular Plasticity
por: Mutsaers, Henricus A. M., et al.
Publicado: (2016)

An animal-free preclinical drug screening platform based on human precision-cut kidney slices
por: Mutsaers, Henricus A. M., et al.
Publicado: (2023)

Vasopressin-Independent Regulation of Aquaporin-2 by Tamoxifen in Kidney Collecting Ducts
por: Tingskov, Stine Julie, et al.
Publicado: (2019)

Predictive Value of Precision-Cut Kidney Slices as an Ex Vivo Screening Platform for Therapeutics in Human Renal Fibrosis
por: Bigaeva, Emilia, et al.
Publicado: (2020)

Renal Interstitial Fibrosis and Angiotensin Inhibition
por: Koo, Ja Wook
Publicado: (2006)

Augmenter of liver regeneration ameliorates renal fibrosis in rats with obstructive nephropathy
por: Chen, Guo-tao, et al.
Publicado: (2014)

miRNA-342 suppresses renal interstitial fibrosis in diabetic nephropathy by targeting SOX6
por: Jiang, Zhen-Huan, et al.
Publicado: (2020)

Inhibitory effects of fasudil on renal interstitial fibrosis induced by unilateral ureteral obstruction
por: BABA, ITSUKO, et al.
Publicado: (2015)

Editorial: Molecular Mechanism and Therapeutic Approach to Renal Interstitial Fibrosis
por: Li, Mao-Ting, et al.
Publicado: (2022)

Circulating TNF Receptors 1 and 2 Are Associated with the Severity of Renal Interstitial Fibrosis in IgA Nephropathy
por: Sonoda, Yuji, et al.
Publicado: (2015)

Iron Chelation by Deferoxamine Prevents Renal Interstitial Fibrosis in Mice with Unilateral Ureteral Obstruction
por: Ikeda, Yasumasa, et al.
Publicado: (2014)

Astaxanthin ameliorates renal interstitial fibrosis and peritubular capillary rarefaction in unilateral ureteral obstruction
por: Zhao, Jin, et al.
Publicado: (2019)

The Pathophysiology and the Management of Radiocontrast-Induced Nephropathy
por: Cho, Eunjung, et al.
Publicado: (2022)

Discovery of Fibrinogen γ-chain as a potential urinary biomarker for renal interstitial fibrosis in IgA nephropathy
por: Guan, Jie, et al.
Publicado: (2023)

Emerging Urinary Markers of Renal Injury in Obstructive Nephropathy
por: Lucarelli, Giuseppe, et al.
Publicado: (2014)

CXCL6 Promotes Renal Interstitial Fibrosis in Diabetic Nephropathy by Activating JAK/STAT3 Signaling Pathway
por: Sun, Meng-Yao, et al.
Publicado: (2019)

Ulinastatin inhibits renal tubular epithelial apoptosis and interstitial fibrosis in rats with unilateral ureteral obstruction
por: Zhang, Qing-Fang
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_knu8qv5vt723cftelb01ts08qu