Conditional blastocyst complementation of a defective Foxa2 lineage efficiently promotes the generation of the whole lung

Millions suffer from incurable lung diseases, and the donor lung shortage hampers organ transplants. Generating the whole organ in conjunction with the thymus is a significant milestone for organ transplantation because the thymus is the central organ to educate immune cells. Using lineage-tracing m...

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Detalles Bibliográficos
Autores principales: Miura, Akihiro, Sarmah, Hemanta, Tanaka, Junichi, Hwang, Youngmin, Sawada, Anri, Shimamura, Yuko, Otoshi, Takehiro, Kondo, Yuri, Fang, Yinshan, Shimizu, Dai, Ninish, Zurab, Suer, Jake Le, Dubois, Nicole C, Davis, Jennifer, Toyooka, Shinichi, Wu, Jun, Que, Jianwen, Hawkins, Finn J, Lin, Chyuan-Sheng, Mori, Munemasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642968/
https://www.ncbi.nlm.nih.gov/pubmed/37861292
http://dx.doi.org/10.7554/eLife.86105

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