Cargando…

GPC3 Promotes Lung Squamous Cell Carcinoma Progression and HLA-A2-Restricted GPC3 Antigenic Peptide-Modified Dendritic Cell-Induced Cytotoxic T Lymphocytes to Kill Lung Squamous Cell Carcinoma Cells

Lung squamous cell carcinoma (LUSC) is associated with poor clinical prognosis and lacks available targeted agents. GPC3 is upregulated in LUSC. Our study aimed to explore the roles of GPC3 in LUSC and the antitumor effects of HLA-A2-restricted GPC3 antigenic peptide-sensitized dendritic cell (DC)-i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ning, Jing, Ding, Jianqiao, Wang, Shu, Jiang, Youhong, Wang, Daqing, Jiang, Shenyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643027/ https://www.ncbi.nlm.nih.gov/pubmed/37965271 http://dx.doi.org/10.1155/2023/5532617

Ejemplares similares

GPC3 affects the prognosis of lung adenocarcinoma and lung squamous cell carcinoma
por: Ning, Jing, et al.
Publicado: (2021)

Correction to: GPC3 affects the prognosis of lung adenocarcinoma and lung squamous cell carcinoma
por: Ning, Jing, et al.
Publicado: (2021)

GPC3 reduces cell proliferation in renal carcinoma cell lines
por: Valsechi, Marina Curado, et al.
Publicado: (2014)

Optimization of GPC3-specific chimeric antigen receptor structure and its effect on killing hepatocellular carcinoma cells
por: Zhao, Jianfeng, et al.
Publicado: (2021)

Treatment of hepatocellular carcinoma with a GPC3-targeted bispecific T cell engager
por: Bi, Yanyu, et al.
Publicado: (2017)

GPC-3 in hepatocellular carcinoma: current perspectives
por: Wu, Yongle, et al.
Publicado: (2016)

Development of anti-GPC-1 (glypican-1)-CAR-T cells for adoptive T cell immunotherapies for squamous cell carcinoma
por: Yaguchi, Tomonori, et al.
Publicado: (2015)

Low glucose metabolism in hepatocellular carcinoma with GPC3 expression
por: Li, You-Cai, et al.
Publicado: (2018)

Combination of AAV-CCL19 and GPC3 CAR-T Cells in the Treatment of Hepatocellular Carcinoma
por: Meng, Min, et al.
Publicado: (2021)

Critical analysis of the potential of targeting GPC3 in hepatocellular carcinoma
por: Ofuji, Kazuya, et al.
Publicado: (2014)

Anti-GPC3-CAR T Cells Suppress the Growth of Tumor Cells in Patient-Derived Xenografts of Hepatocellular Carcinoma
por: Jiang, Zhiwu, et al.
Publicado: (2017)

GPC6 Promotes Cell Proliferation, Migration, and Invasion in Nasopharyngeal Carcinoma
por: Fan, Chunmei, et al.
Publicado: (2019)

Recombinant immunotoxin targeting GPC3 is cytotoxic to H446 small cell lung cancer cells
por: Rodakowska, Ewelina, et al.
Publicado: (2021)

Preparation and Characterization of Anti-GPC3 Nanobody Against Hepatocellular Carcinoma
por: Xia, Lijie, et al.
Publicado: (2020)

Elevated GPC3 level promotes cell proliferation in liver cancer
por: Wang, Shanshan, et al.
Publicado: (2018)

Bispecific GPC3/PD-1 CAR-T cells for the treatment of HCC
por: Li, Dezhi, et al.
Publicado: (2023)

A GPC3-specific aptamer-mediated magnetic resonance probe for hepatocellular carcinoma
por: Zhao, Menglong, et al.
Publicado: (2018)

Glypican-3 (GPC3) is associated with MCPyV-negative status and impaired outcome in Merkel cell carcinoma
por: Muralidharan, Sujatha, et al.
Publicado: (2022)

Natural killer cells modified with a Gpc3 aptamer enhance adoptive immunotherapy for hepatocellular carcinoma
por: Zheng, Youshi, et al.
Publicado: (2023)

ENGINEERING T CELLS TARGETING GPC2 FOR TREATING NEUROBLASTOMA
por: Quan, Alex, et al.
Publicado: (2023)

Targeted Therapy of Hepatocellular Carcinoma Using Gemcitabine-Incorporated GPC3 Aptamer
por: Park, Jun Young, et al.
Publicado: (2020)

miR-96 promotes invasion and metastasis by targeting GPC3 in non-small cell lung cancer cells
por: Fei, Xiubin, et al.
Publicado: (2018)

GPC3 expression in mouse ovarian cancer induces GPC3-specific T cell-mediated immune response through M1 macrophages and suppresses tumor growth
por: LUO, CHENHONG, et al.
Publicado: (2014)

Phosphorothioate-Modified AP613-1 Specifically Targets GPC3 when Used for Hepatocellular Carcinoma Cell Imaging
por: Dong, Lili, et al.
Publicado: (2018)

Clinical values of AFP, GPC3 mRNA in peripheral blood for prediction of hepatocellular carcinoma recurrence following OLT: AFP, GPC3 mRNA for prediction of HCC
por: Wang, Yuliang, et al.
Publicado: (2011)

GPC3-Unc5 receptor complex structure and role in cell migration
por: Akkermans, Onno, et al.
Publicado: (2022)

The clinical significance of CTC enrichment by GPC3-IML and its genetic analysis in hepatocellular carcinoma
por: Yi, Bin, et al.
Publicado: (2021)

Structure based innovative approach to analyze aptaprobe–GPC3 complexes in hepatocellular carcinoma
por: Shin, Woo-Ri, et al.
Publicado: (2022)

Somatic glypican 3 (GPC3) mutations in Wilms' tumour
por: White, G R M, et al.
Publicado: (2002)

Correction to: The clinical significance of CTC enrichment by GPC3-IML and its genetic analysis in hepatocellular carcinoma
por: Yi, Bin, et al.
Publicado: (2021)

Immunotherapeutic Targeting of GPC3 in Pediatric Solid Embryonal Tumors
por: Ortiz, Michael V., et al.
Publicado: (2019)

Significance of Glypican-3 (GPC3) Expression in Hepatocellular Cancer Diagnosis
por: Sun, Bin, et al.
Publicado: (2017)

GPC2 deficiency inhibits cell growth and metastasis in colon adenocarcinoma
por: Lin, Lumin, et al.
Publicado: (2022)

HMGB1/GPC3 dual targeting vaccine induces dendritic cells-mediated CD8(+)T cell immune response and elicits potential therapeutic effect in hepatocellular carcinoma
por: Shi, Xiaoqing, et al.
Publicado: (2023)

Combined local therapy and CAR‐GPC3 T‐cell therapy in advanced hepatocellular carcinoma: a proof‐of‐concept treatment strategy
por: Shi, Yaoping, et al.
Publicado: (2023)

Glypican-3 (GPC-3) Structural Analysis and Cargo in Serum Small Extracellular Vesicles of Hepatocellular Carcinoma Patients
por: Mauro, Montalbano, et al.
Publicado: (2023)

Phase II study of the GPC3-derived peptide vaccine as an adjuvant therapy for hepatocellular carcinoma patients
por: Sawada, Yu, et al.
Publicado: (2016)

Highly Potent Immunotoxins Targeting the Membrane-distal N-lobe of GPC3 for Immunotherapy of Hepatocellular Carcinoma
por: Li, Jingwen, et al.
Publicado: (2022)

GPC3 gene expression and allelic discrimination of FZD7 gene in Egyptian patients with hepatocellular carcinoma
por: Ramadan, Amany, et al.
Publicado: (2023)

Anti-GPC3 antibody-modified sorafenib-loaded nanoparticles significantly inhibited HepG2 hepatocellular carcinoma
por: Tang, Xiaolong, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_bfniiub4a5po6oumhslgioqs12