Cargando…
Platelet Receptor Glycoprotein VI-Dimer Is Overexpressed in Patients with Atrial Fibrillation at High Risk of Ischemic Stroke
Introduction Atrial fibrillation (AF) increases the risk of ischemic stroke (IS). We hypothesized that the functional form of platelet receptor glycoprotein (GP) VI, GPVI-dimer, which binds to collagen and fibrin causing platelet activation, is overexpressed in patients with AF who have not had a s...
Autores principales: | Induruwa, Isuru, Kempster, Carly, Thomas, Patrick, McKinney, Harriet, Malcor, Jean-Daniel, Bonna, Arkadiusz, Batista, Joana, Soejima, Kenji, Ouwehand, Willem, Farndale, Richard W., Downes, Kate, Moroi, Masaaki, Jung, Stephanie M., Warburton, Elizabeth A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Georg Thieme Verlag KG
2023
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643047/ https://www.ncbi.nlm.nih.gov/pubmed/37964899 http://dx.doi.org/10.1055/s-0043-1776328 |
Ejemplares similares
-
Platelet surface receptor glycoprotein VI-dimer is overexpressed in stroke: The Glycoprotein VI in Stroke (GYPSIE) study results
por: Induruwa, Isuru, et al.
Publicado: (2022) -
Platelet collagen receptor Glycoprotein VI‐dimer recognizes fibrinogen and fibrin through their D‐domains, contributing to platelet adhesion and activation during thrombus formation
por: Induruwa, I., et al.
Publicado: (2018) -
Factor XIII is a newly identified binding partner for platelet collagen receptor GPVI‐dimer—An interaction that may modulate fibrin crosslinking
por: Moroi, Masaaki, et al.
Publicado: (2022) -
Beyond antiplatelets: The role of glycoprotein VI in ischemic stroke
por: Induruwa, Isuru, et al.
Publicado: (2016) -
Constitutive Dimerization of Glycoprotein VI (GPVI) in Resting Platelets Is Essential for Binding to Collagen and Activation in Flowing Blood
por: Jung, Stephanie M., et al.
Publicado: (2012)