Live-cell three-dimensional single-molecule tracking reveals modulation of enhancer dynamics by NuRD

To understand how the nucleosome remodeling and deacetylase (NuRD) complex regulates enhancers and enhancer–promoter interactions, we have developed an approach to segment and extract key biophysical parameters from live-cell three-dimensional single-molecule trajectories. Unexpectedly, this has rev...

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Detalles Bibliográficos
Autores principales: Basu, S., Shukron, O., Hall, D., Parutto, P., Ponjavic, A., Shah, D., Boucher, W., Lando, D., Zhang, W., Reynolds, N., Sober, L. H., Jartseva, A., Ragheb, R., Ma, X., Cramard, J., Floyd, R., Balmer, J., Drury, T. A., Carr, A. R., Needham, L.-M., Aubert, A., Communie, G., Gor, K., Steindel, M., Morey, L., Blanco, E., Bartke, T., Di Croce, L., Berger, I., Schaffitzel, C., Lee, S. F., Stevens, T. J., Klenerman, D., Hendrich, B. D., Holcman, D., Laue, E. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643137/
https://www.ncbi.nlm.nih.gov/pubmed/37770717
http://dx.doi.org/10.1038/s41594-023-01095-4

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