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Melanocortin-4 receptor in macrophages attenuated angiotensin II-induced abdominal aortic aneurysm in mice

Obesity is recognized as an independent risk factor for abdominal aortic aneurysm (AAA). While mutations in the melanocortin-4 receptor (MC4R) gene is the most common cause of obesity caused by mutations in a single gene, the link between MC4R function and vascular disease has still remained unclear...

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Detalles Bibliográficos
Autores principales: Mori, Kentaro, Okuma, Hideyuki, Nakamura, Suguru, Uchinuma, Hiroyuki, Kaga, Shigeaki, Nakajima, Hiroyuki, Ogawa, Yoshihiro, Tsuchiya, Kyoichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643430/
https://www.ncbi.nlm.nih.gov/pubmed/37957201
http://dx.doi.org/10.1038/s41598-023-46831-4