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Melanocortin-4 receptor in macrophages attenuated angiotensin II-induced abdominal aortic aneurysm in mice
Obesity is recognized as an independent risk factor for abdominal aortic aneurysm (AAA). While mutations in the melanocortin-4 receptor (MC4R) gene is the most common cause of obesity caused by mutations in a single gene, the link between MC4R function and vascular disease has still remained unclear...
Autores principales: | Mori, Kentaro, Okuma, Hideyuki, Nakamura, Suguru, Uchinuma, Hiroyuki, Kaga, Shigeaki, Nakajima, Hiroyuki, Ogawa, Yoshihiro, Tsuchiya, Kyoichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643430/ https://www.ncbi.nlm.nih.gov/pubmed/37957201 http://dx.doi.org/10.1038/s41598-023-46831-4 |
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