Cargando…

Sexual dimorphic metabolic and cognitive responses of C57BL/6 mice to Fisetin or Dasatinib and quercetin cocktail oral treatment

Senolytic treatment in aged mice clears senescent cell burden leading to functional improvements. However, less is known regarding the effects of these compounds when administered prior to significant senescent cell accumulation. From 4–13 months of age, C57BL/6 male and female mice received monthly...

Descripción completa

Detalles Bibliográficos
Autores principales: Fang, Yimin, Medina, David, Stockwell, Robert, McFadden, Sam, Quinn, Kathleen, Peck, Mackenzie R., Bartke, Andrzej, Hascup, Kevin N., Hascup, Erin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643448/
https://www.ncbi.nlm.nih.gov/pubmed/37296266
http://dx.doi.org/10.1007/s11357-023-00843-0