RNA m(6)A methylation modulates airway inflammation in allergic asthma via PTX3-dependent macrophage homeostasis

N(6)-methyladenosine (m(6)A), the most prevalent mRNA modification, has an important function in diverse biological processes. However, the involvement of m(6)A in allergic asthma and macrophage homeostasis remains largely unknown. Here we show that m(6)A methyltransferases METTL3 is expressed at a...

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Detalles Bibliográficos
Autores principales: Han, Xiao, Liu, Lijuan, Huang, Saihua, Xiao, Wenfeng, Gao, Yajing, Zhou, Weitao, Zhang, Caiyan, Zheng, Hongmei, Yang, Lan, Xie, Xueru, Liang, Qiuyan, Tu, Zikun, Yu, Hongmiao, Fu, Jinrong, Wang, Libo, Zhang, Xiaobo, Qian, Liling, Zhou, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643624/
https://www.ncbi.nlm.nih.gov/pubmed/37957139
http://dx.doi.org/10.1038/s41467-023-43219-w

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