Local membrane source gathering by p62 body drives autophagosome formation

Autophagosomes are double-membrane vesicles generated intracellularly to encapsulate substrates for lysosomal degradation during autophagy. Phase separated p62 body plays pivotal roles during autophagosome formation, however, the underlying mechanisms are still not fully understood. Here we describe...

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Detalles Bibliográficos
Autores principales: Feng, Xuezhao, Sun, Daxiao, Li, Yanchang, Zhang, Jinpei, Liu, Shiyu, Zhang, Dachuan, Zheng, Jingxiang, Xi, Qing, Liang, Haisha, Zhao, Wenkang, Li, Ying, Xu, Mengbo, He, Jiayu, Liu, Tong, Hasim, Ayshamgul, Ma, Meisheng, Xu, Ping, Mi, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643672/
https://www.ncbi.nlm.nih.gov/pubmed/37957156
http://dx.doi.org/10.1038/s41467-023-42829-8

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