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Vascular senescence and leak are features of the early breakdown of the blood–brain barrier in Alzheimer’s disease models
Alzheimer’s disease (AD) is an age-related disease, with loss of integrity of the blood–brain barrier (BBB) being an early feature. Cellular senescence is one of the reported nine hallmarks of aging. Here, we show for the first time the presence of senescent cells in the vasculature in AD patients a...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643714/ https://www.ncbi.nlm.nih.gov/pubmed/37782439 http://dx.doi.org/10.1007/s11357-023-00927-x |