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Immune microenvironment dynamics of HER2 overexpressing breast cancer under dual anti-HER2 blockade

INTRODUCTION: The clinical prognosis of the HER2-overexpressing (HER2-OE) subtype of breast cancer (BC) is influenced by the immune infiltrate of the tumor. Specifically, monocytic cells, which are promoters of pro-tumoral immunosuppression, and NK cells, whose basal cytotoxic function may be enhanc...

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Detalles Bibliográficos
Autores principales: Batalha, Sofia, Gomes, Catarina Monteiro, Brito, Catarina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643871/
https://www.ncbi.nlm.nih.gov/pubmed/38022643
http://dx.doi.org/10.3389/fimmu.2023.1267621