Case study of semaglutide and cardiovascular outcomes: An application of the Causal Roadmap to a hybrid design for augmenting an RCT control arm with real-world data

INTRODUCTION: Increasing interest in real-world evidence has fueled the development of study designs incorporating real-world data (RWD). Using the Causal Roadmap, we specify three designs to evaluate the difference in risk of major adverse cardiovascular events (MACE) with oral semaglutide versus s...

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Detalles Bibliográficos
Autores principales: Dang, Lauren E., Fong, Edwin, Tarp, Jens Magelund, Clemmensen, Kim Katrine Bjerring, Ravn, Henrik, Kvist, Kajsa, Buse, John B., van der Laan, Mark, Petersen, Maya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643919/
https://www.ncbi.nlm.nih.gov/pubmed/38028337
http://dx.doi.org/10.1017/cts.2023.656

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