Entinostat Enhances the Efficacy of Chemotherapy in Small Cell Lung Cancer Through S-phase Arrest and Decreased Base Excision Repair

PURPOSE: Acquired chemoresistance is a frequent event in small cell lung cancer (SCLC), one of the deadliest human malignancies. Histone deacetylase inhibitors (HDACi) have been shown to synergize with different chemotherapeutic agents including cisplatin. Accordingly, we aimed to investigate the du...

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Detalles Bibliográficos
Autores principales: Solta, Anna, Boettiger, Kristiina, Kovács, Ildikó, Lang, Christian, Megyesfalvi, Zsolt, Ferk, Franziska, Mišík, Miroslav, Hoetzenecker, Konrad, Aigner, Clemens, Kowol, Christian R., Knasmueller, Siegfried, Grusch, Michael, Szeitz, Beáta, Rezeli, Melinda, Dome, Balazs, Schelch, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Translational Cancer Mechanisms and Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644001/
https://www.ncbi.nlm.nih.gov/pubmed/37725585
http://dx.doi.org/10.1158/1078-0432.CCR-23-1795

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644001/
https://www.ncbi.nlm.nih.gov/pubmed/37725585
http://dx.doi.org/10.1158/1078-0432.CCR-23-1795

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