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Temperature control in sepsis

Fever can be viewed as an adaptive response to infection. Temperature control in sepsis is aimed at preventing potential harms associated with high temperature (tachycardia, vasodilation, electrolyte and water loss) and therapeutic hypothermia may be aimed at slowing metabolic activities and protect...

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Autores principales: Doman, Marc, Thy, Michael, Dessajan, Julien, Dlela, Mariem, Do Rego, Hermann, Cariou, Erwann, Ejzenberg, Michael, Bouadma, Lila, de Montmollin, Etienne, Timsit, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644266/
https://www.ncbi.nlm.nih.gov/pubmed/38020082
http://dx.doi.org/10.3389/fmed.2023.1292468
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author Doman, Marc
Thy, Michael
Dessajan, Julien
Dlela, Mariem
Do Rego, Hermann
Cariou, Erwann
Ejzenberg, Michael
Bouadma, Lila
de Montmollin, Etienne
Timsit, Jean-François
author_facet Doman, Marc
Thy, Michael
Dessajan, Julien
Dlela, Mariem
Do Rego, Hermann
Cariou, Erwann
Ejzenberg, Michael
Bouadma, Lila
de Montmollin, Etienne
Timsit, Jean-François
author_sort Doman, Marc
collection PubMed
description Fever can be viewed as an adaptive response to infection. Temperature control in sepsis is aimed at preventing potential harms associated with high temperature (tachycardia, vasodilation, electrolyte and water loss) and therapeutic hypothermia may be aimed at slowing metabolic activities and protecting organs from inflammation. Although high fever (>39.5°C) control is usually performed in critically ill patients, available cohorts and randomized controlled trials do not support its use to improve sepsis prognosis. Finally, both spontaneous and therapeutic hypothermia are associated with poor outcomes in sepsis.
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spelling pubmed-106442662023-10-31 Temperature control in sepsis Doman, Marc Thy, Michael Dessajan, Julien Dlela, Mariem Do Rego, Hermann Cariou, Erwann Ejzenberg, Michael Bouadma, Lila de Montmollin, Etienne Timsit, Jean-François Front Med (Lausanne) Medicine Fever can be viewed as an adaptive response to infection. Temperature control in sepsis is aimed at preventing potential harms associated with high temperature (tachycardia, vasodilation, electrolyte and water loss) and therapeutic hypothermia may be aimed at slowing metabolic activities and protecting organs from inflammation. Although high fever (>39.5°C) control is usually performed in critically ill patients, available cohorts and randomized controlled trials do not support its use to improve sepsis prognosis. Finally, both spontaneous and therapeutic hypothermia are associated with poor outcomes in sepsis. Frontiers Media S.A. 2023-10-31 /pmc/articles/PMC10644266/ /pubmed/38020082 http://dx.doi.org/10.3389/fmed.2023.1292468 Text en Copyright © 2023 Doman, Thy, Dessajan, Dlela, Do Rego, Cariou, Ejzenberg, Bouadma, de Montmollin and Timsit. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Doman, Marc
Thy, Michael
Dessajan, Julien
Dlela, Mariem
Do Rego, Hermann
Cariou, Erwann
Ejzenberg, Michael
Bouadma, Lila
de Montmollin, Etienne
Timsit, Jean-François
Temperature control in sepsis
title Temperature control in sepsis
title_full Temperature control in sepsis
title_fullStr Temperature control in sepsis
title_full_unstemmed Temperature control in sepsis
title_short Temperature control in sepsis
title_sort temperature control in sepsis
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644266/
https://www.ncbi.nlm.nih.gov/pubmed/38020082
http://dx.doi.org/10.3389/fmed.2023.1292468
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