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Skeletal muscle proteome analysis underpins multifaceted mitochondrial dysfunction in Friedreich’s ataxia

Friedreich’s ataxia (FRDA) is a severe multisystemic disorder caused by a deficiency of the mitochondrial protein frataxin. While some aspects of FRDA pathology are developmental, the causes underlying the steady progression are unclear. The inaccessibility of key affected tissues to sampling is a m...

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Detalles Bibliográficos
Autores principales:	Indelicato, Elisabetta, Faserl, Klaus, Amprosi, Matthias, Nachbauer, Wolfgang, Schneider, Rainer, Wanschitz, Julia, Sarg, Bettina, Boesch, Sylvia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644315/ https://www.ncbi.nlm.nih.gov/pubmed/38027498 http://dx.doi.org/10.3389/fnins.2023.1289027

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