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Prebiotics: Ignored player in the fight against cancer

BACKGROUND: Prebiotics is a relatively neglected area in cancer research, despite evidence suggesting that it plays a key role in suppressing tumour growth and improving immune function. RECENT FINDINGS: Including prebiotics in the diet has been shown to strengthen the immune system and can better s...

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Autores principales: Mishra, Parichita, Badiyani, Vidhi Manish, Jain, Sakshi, Subramanian, Sruti, Maharaj, Sakshee Vinay, Kumar, Ashwini, Singh, Bhisham Narayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644333/
https://www.ncbi.nlm.nih.gov/pubmed/37458148
http://dx.doi.org/10.1002/cnr2.1870
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author Mishra, Parichita
Badiyani, Vidhi Manish
Jain, Sakshi
Subramanian, Sruti
Maharaj, Sakshee Vinay
Kumar, Ashwini
Singh, Bhisham Narayan
author_facet Mishra, Parichita
Badiyani, Vidhi Manish
Jain, Sakshi
Subramanian, Sruti
Maharaj, Sakshee Vinay
Kumar, Ashwini
Singh, Bhisham Narayan
author_sort Mishra, Parichita
collection PubMed
description BACKGROUND: Prebiotics is a relatively neglected area in cancer research, despite evidence suggesting that it plays a key role in suppressing tumour growth and improving immune function. RECENT FINDINGS: Including prebiotics in the diet has been shown to strengthen the immune system and can better slow down or prevent the growth of tumours. It has also been strongly indicated in various scientific studies that prebiotics can contribute to the sustenance of a healthy microbiome, which in turn plays an important role in increasing the effectiveness and reducing the side effects of cancer treatments. CONCLUSION: In the present review article we highlight the mechanisms by which prebiotics like inulin, fructooligosaccharide (FOS), β‐glucan, pectin, and xylooligosaccharide (XOS) function. Furthermore, the beneficial effect of incorporating prebiotics during cancer therapy to improvise gut health and prevent/reverse the damage caused to patients due to chemotherapy has also been elaborated.
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spelling pubmed-106443332023-11-15 Prebiotics: Ignored player in the fight against cancer Mishra, Parichita Badiyani, Vidhi Manish Jain, Sakshi Subramanian, Sruti Maharaj, Sakshee Vinay Kumar, Ashwini Singh, Bhisham Narayan Cancer Rep (Hoboken) Reviews BACKGROUND: Prebiotics is a relatively neglected area in cancer research, despite evidence suggesting that it plays a key role in suppressing tumour growth and improving immune function. RECENT FINDINGS: Including prebiotics in the diet has been shown to strengthen the immune system and can better slow down or prevent the growth of tumours. It has also been strongly indicated in various scientific studies that prebiotics can contribute to the sustenance of a healthy microbiome, which in turn plays an important role in increasing the effectiveness and reducing the side effects of cancer treatments. CONCLUSION: In the present review article we highlight the mechanisms by which prebiotics like inulin, fructooligosaccharide (FOS), β‐glucan, pectin, and xylooligosaccharide (XOS) function. Furthermore, the beneficial effect of incorporating prebiotics during cancer therapy to improvise gut health and prevent/reverse the damage caused to patients due to chemotherapy has also been elaborated. John Wiley and Sons Inc. 2023-07-17 /pmc/articles/PMC10644333/ /pubmed/37458148 http://dx.doi.org/10.1002/cnr2.1870 Text en © 2023 The Authors. Cancer Reports published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Reviews
Mishra, Parichita
Badiyani, Vidhi Manish
Jain, Sakshi
Subramanian, Sruti
Maharaj, Sakshee Vinay
Kumar, Ashwini
Singh, Bhisham Narayan
Prebiotics: Ignored player in the fight against cancer
title Prebiotics: Ignored player in the fight against cancer
title_full Prebiotics: Ignored player in the fight against cancer
title_fullStr Prebiotics: Ignored player in the fight against cancer
title_full_unstemmed Prebiotics: Ignored player in the fight against cancer
title_short Prebiotics: Ignored player in the fight against cancer
title_sort prebiotics: ignored player in the fight against cancer
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644333/
https://www.ncbi.nlm.nih.gov/pubmed/37458148
http://dx.doi.org/10.1002/cnr2.1870
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