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Prebiotics: Ignored player in the fight against cancer
BACKGROUND: Prebiotics is a relatively neglected area in cancer research, despite evidence suggesting that it plays a key role in suppressing tumour growth and improving immune function. RECENT FINDINGS: Including prebiotics in the diet has been shown to strengthen the immune system and can better s...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644333/ https://www.ncbi.nlm.nih.gov/pubmed/37458148 http://dx.doi.org/10.1002/cnr2.1870 |
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author | Mishra, Parichita Badiyani, Vidhi Manish Jain, Sakshi Subramanian, Sruti Maharaj, Sakshee Vinay Kumar, Ashwini Singh, Bhisham Narayan |
author_facet | Mishra, Parichita Badiyani, Vidhi Manish Jain, Sakshi Subramanian, Sruti Maharaj, Sakshee Vinay Kumar, Ashwini Singh, Bhisham Narayan |
author_sort | Mishra, Parichita |
collection | PubMed |
description | BACKGROUND: Prebiotics is a relatively neglected area in cancer research, despite evidence suggesting that it plays a key role in suppressing tumour growth and improving immune function. RECENT FINDINGS: Including prebiotics in the diet has been shown to strengthen the immune system and can better slow down or prevent the growth of tumours. It has also been strongly indicated in various scientific studies that prebiotics can contribute to the sustenance of a healthy microbiome, which in turn plays an important role in increasing the effectiveness and reducing the side effects of cancer treatments. CONCLUSION: In the present review article we highlight the mechanisms by which prebiotics like inulin, fructooligosaccharide (FOS), β‐glucan, pectin, and xylooligosaccharide (XOS) function. Furthermore, the beneficial effect of incorporating prebiotics during cancer therapy to improvise gut health and prevent/reverse the damage caused to patients due to chemotherapy has also been elaborated. |
format | Online Article Text |
id | pubmed-10644333 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-106443332023-11-15 Prebiotics: Ignored player in the fight against cancer Mishra, Parichita Badiyani, Vidhi Manish Jain, Sakshi Subramanian, Sruti Maharaj, Sakshee Vinay Kumar, Ashwini Singh, Bhisham Narayan Cancer Rep (Hoboken) Reviews BACKGROUND: Prebiotics is a relatively neglected area in cancer research, despite evidence suggesting that it plays a key role in suppressing tumour growth and improving immune function. RECENT FINDINGS: Including prebiotics in the diet has been shown to strengthen the immune system and can better slow down or prevent the growth of tumours. It has also been strongly indicated in various scientific studies that prebiotics can contribute to the sustenance of a healthy microbiome, which in turn plays an important role in increasing the effectiveness and reducing the side effects of cancer treatments. CONCLUSION: In the present review article we highlight the mechanisms by which prebiotics like inulin, fructooligosaccharide (FOS), β‐glucan, pectin, and xylooligosaccharide (XOS) function. Furthermore, the beneficial effect of incorporating prebiotics during cancer therapy to improvise gut health and prevent/reverse the damage caused to patients due to chemotherapy has also been elaborated. John Wiley and Sons Inc. 2023-07-17 /pmc/articles/PMC10644333/ /pubmed/37458148 http://dx.doi.org/10.1002/cnr2.1870 Text en © 2023 The Authors. Cancer Reports published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Reviews Mishra, Parichita Badiyani, Vidhi Manish Jain, Sakshi Subramanian, Sruti Maharaj, Sakshee Vinay Kumar, Ashwini Singh, Bhisham Narayan Prebiotics: Ignored player in the fight against cancer |
title | Prebiotics: Ignored player in the fight against cancer |
title_full | Prebiotics: Ignored player in the fight against cancer |
title_fullStr | Prebiotics: Ignored player in the fight against cancer |
title_full_unstemmed | Prebiotics: Ignored player in the fight against cancer |
title_short | Prebiotics: Ignored player in the fight against cancer |
title_sort | prebiotics: ignored player in the fight against cancer |
topic | Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644333/ https://www.ncbi.nlm.nih.gov/pubmed/37458148 http://dx.doi.org/10.1002/cnr2.1870 |
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