Cargando…

Aging and the impact of global DNA methylation, telomere shortening, and total oxidative status on sarcopenia and frailty syndrome

Aging is a biological event that influences many organs and systems. Both sarcopenia and frailty syndrome refer to geriatric conditions with overlapping phenotypes. Many mechanisms are involved in the aging process such as DNA methylation telomeres which are susceptible to oxidative stress, and infl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kmiołek, Tomasz, Filipowicz, Gabriela, Bogucka, Diana, Wajda, Anna, Ejma-Multański, Adam, Stypińska, Barbara, Modzelewska, Ewa, Kaliberda, Yana, Radkowski, Marcin, Targowski, Tomasz, Wrona, Julia, Paradowska-Gorycka, Agnieszka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644469/ https://www.ncbi.nlm.nih.gov/pubmed/37964387 http://dx.doi.org/10.1186/s12979-023-00384-2

Ejemplares similares

Expression of Prostaglandin Genes and β-Catenin in Whole Blood as Potential Markers of Muscle Degeneration
por: Wajda, Anna, et al.
Publicado: (2023)

Cell Cultures as a Versatile Tool in the Research and Treatment of Autoimmune Connective Tissue Diseases
por: Ejma-Multański, Adam, et al.
Publicado: (2023)

Mixed Connective Tissue Disease as Different Entity: Global Methylation Aspect
por: Filipowicz, Gabriela, et al.
Publicado: (2023)

miR-10 and Its Negative Correlation with Serum IL-35 Concentration and Positive Correlation with STAT5a Expression in Patients with Rheumatoid Arthritis
por: Paradowska-Gorycka, Agnieszka, et al.
Publicado: (2022)

miRNAs as Biomarkers and Possible Therapeutic Strategies in Rheumatoid Arthritis
por: Kmiołek, Tomasz, et al.
Publicado: (2022)

The Interplay between Transcriptional Factors and MicroRNAs as an Important Factor for Th17/Treg Balance in RA Patients
por: Kmiołek, Tomasz, et al.
Publicado: (2020)

Th17/Treg-Related Transcriptional Factor Expression and Cytokine Profile in Patients With Rheumatoid Arthritis
por: Paradowska-Gorycka, Agnieszka, et al.
Publicado: (2020)

Oxidative Stress, Telomere Shortening, and Apoptosis Associated to Sarcopenia and Frailty in Patients with Multimorbidity
por: Bernabeu-Wittel, Máximo, et al.
Publicado: (2020)

Cytokines and MicroRNAs as Candidate Biomarkers for Systemic Lupus Erythematosus
por: Stypińska, Barbara, et al.
Publicado: (2015)

The role of cell-free circulating microRNA in diagnostics in patients with rheumatoid arthritis
por: Paradowska-Gorycka, Agnieszka, et al.
Publicado: (2016)

The Serum Cell-Free microRNA Expression Profile in MCTD, SLE, SSc, and RA Patients
por: Stypinska, Barbara, et al.
Publicado: (2020)

AHR-dependent genes and response to MTX therapy in rheumatoid arthritis patients
por: Wajda, Anna, et al.
Publicado: (2021)

Osteosarcopenia in rheumatoid arthritis treated with glucocorticosteroids – essence, significance, consequences
por: Radkowski, Marcin Jerzy, et al.
Publicado: (2020)

Osteoarthritis and telomere shortening
por: Kuszel, Lukasz, et al.
Publicado: (2014)

How the gut microbiota contributes to changes of autoimmune phenotype – from molecular studies to clinical utility
por: Paradowska-Gorycka, Agnieszka, et al.
Publicado: (2020)

Mixed-etiology leg ulcers in a patient on long-term glucocorticoid therapy
por: Sławiński, Piotr, et al.
Publicado: (2019)

Lack of significant association between selected STAT3 polymorphisms and rheumatoid arthritis in the Polish population
por: Stypińska, Barbara, et al.
Publicado: (2018)

Interferons (IFN-A/-B/-G) Genetic Variants in Patients with Mixed Connective Tissue Disease (MCTD)
por: Paradowska-Gorycka, Agnieszka, et al.
Publicado: (2019)

Application of NGS Technology in Understanding the Pathology of Autoimmune Diseases
por: Wajda, Anna, et al.
Publicado: (2021)

Serum microRNAs in Systemic Sclerosis, Associations with Digital Vasculopathy and Lung Involvement
por: Wajda, Anna, et al.
Publicado: (2022)

Epigenetic Regulations of AhR in the Aspect of Immunomodulation
por: Wajda, Anna, et al.
Publicado: (2020)

Pharmacogenomics of Anti-TNF Treatment Response Marks a New Era of Tailored Rheumatoid Arthritis Therapy
por: Wysocki, Tomasz, et al.
Publicado: (2022)

Association study between immune-related miRNAs and mixed connective tissue disease
por: Stypińska, Barbara, et al.
Publicado: (2021)

Some clarifications of terminology may facilitate sarcopenia assessment
por: Lewandowicz, Andrzej, et al.
Publicado: (2019)

Mesenchymal stem cells in systemic sclerosis therapy
por: Dudek, Daniel Witold, et al.
Publicado: (2020)

Current Understanding of an Emerging Role of HLA-DRB1 Gene in Rheumatoid Arthritis–From Research to Clinical Practice
por: Wysocki, Tomasz, et al.
Publicado: (2020)

RORC2 Genetic Variants and Serum Levels in Patients with Rheumatoid Arthritis
por: Paradowska-Gorycka, Agnieszka, et al.
Publicado: (2016)

KDR (VEGFR2) Genetic Variants and Serum Levels in Patients with Rheumatoid Arthritis
por: Paradowska-Gorycka, Agnieszka, et al.
Publicado: (2019)

Accelerated Telomere Shortening in Acromegaly; IGF-I Induces Telomere Shortening and Cellular Senescence
por: Matsumoto, Ryusaku, et al.
Publicado: (2015)

Revisiting Telomere Shortening in Cancer
por: Okamoto, Keiji, et al.
Publicado: (2019)

Relationship between VEGF Gene Polymorphisms and Serum VEGF Protein Levels in Patients with Rheumatoid Arthritis
por: Paradowska-Gorycka, Agnieszka, et al.
Publicado: (2016)

FLT-1 gene polymorphisms and protein expression profile in rheumatoid arthritis
por: Paradowska-Gorycka, Agnieszka, et al.
Publicado: (2017)

Telomere shortening in leukocyte subpopulations in depression
por: Karabatsiakis, Alexander, et al.
Publicado: (2014)

The Importance of Telomere Shortening for Atherosclerosis and Mortality
por: Herrmann, Wolfgang, et al.
Publicado: (2020)

Role of Telomeres Shortening in Atherogenesis: An Overview
por: Yegorov, Yegor E., et al.
Publicado: (2021)

Telomere shortening impairs alveolar regeneration
por: Zhang, Xin, et al.
Publicado: (2022)

U1-RNP and TLR receptors in the pathogenesis of mixed connective tissue disease Part I. The U1-RNP complex and its biological significance in the pathogenesis of mixed connective tissue disease
por: Paradowska-Gorycka, Agnieszka
Publicado: (2015)

U1-RNP and Toll-like receptors in the pathogenesis of mixed connective tissue disease Part II. Endosomal TLRs and their biological significance in the pathogenesis of mixed connective tissue disease
por: Paradowska-Gorycka, Agnieszka
Publicado: (2015)

Telomere shortening and telomere position effect in mild ring 17 syndrome
por: Surace, Cecilia, et al.
Publicado: (2014)

Low ALT, a marker of sarcopenia and frailty, is associated with shortened survival amongst myelodysplastic syndrome patients: A retrospective study
por: Uliel, Noa, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_l94iqo10cg56v6atgl2nqf5bjk