Spatial transcriptomics and neurofilament light chain reveal changes in lesion patterns in murine autoimmune neuroinflammation

OBJECTIVE: Ongoing neuroaxonal damage is a major contributor to disease progression and long-term disability in multiple sclerosis. However, spatio-temporal distribution and pathophysiological mechanisms of neuroaxonal damage during acute relapses and later chronic disease stages remain poorly under...

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Detalles Bibliográficos
Autores principales: Brummer, Tobias, Schillner, Miriam, Steffen, Falk, Kneilmann, Flores, Wasser, Beatrice, Uphaus, Timo, Zipp, Frauke, Bittner, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644497/
https://www.ncbi.nlm.nih.gov/pubmed/37957728
http://dx.doi.org/10.1186/s12974-023-02947-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644497/
https://www.ncbi.nlm.nih.gov/pubmed/37957728
http://dx.doi.org/10.1186/s12974-023-02947-y

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