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A mouse model of ATRX deficiency with cognitive deficits and autistic traits
BACKGROUND: ATRX is an ATP-dependent chromatin remodeling protein with essential roles in safeguarding genome integrity and modulating gene expression. Deficiencies in this protein cause ATR-X syndrome, a condition characterized by intellectual disability and an array of developmental abnormalities,...
Autores principales: | Quesnel, Katherine M., Martin-Kenny, Nicole, Bérubé, Nathalie G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644498/ https://www.ncbi.nlm.nih.gov/pubmed/37957569 http://dx.doi.org/10.1186/s11689-023-09508-7 |
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