Comparative immunological landscape between pre- and early-stage LUAD manifested as ground-glass nodules revealed by scRNA and scTCR integrated analysis

BACKGROUND: Mechanism underlying the malignant progression of precancer to early-stage lung adenocarcinoma (LUAD) as well as their indolence nature remains elusive. METHODS: Single-cell RNA sequencing (scRNA) with simultaneous T cell receptor (TCR) sequencing on 5 normal lung tissues, 3 precancerous...

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Detalles Bibliográficos
Autores principales: Wang, Ziqi, Yang, Li, Wang, Wenqiang, Zhou, Huanhuan, Chen, Juan, Ma, Zeheng, Wang, Xiaoyan, Zhang, Quncheng, Liu, Haiyang, Zhou, Chao, Guo, Zhiping, Zhang, Xiaoju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644515/
https://www.ncbi.nlm.nih.gov/pubmed/37957625
http://dx.doi.org/10.1186/s12964-023-01322-x

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