Removal of a partial genomic duplication restores synaptic transmission and behavior in the MyosinVA mutant mouse Flailer

BACKGROUND: Copy number variations, and particularly duplications of genomic regions, have been strongly associated with various neurodegenerative conditions including autism spectrum disorder (ASD). These genetic variations have been found to have a significant impact on brain development and funct...

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Detalles Bibliográficos
Autores principales: Bustos, Fernando J., Pandian, Swarna, Haensgen, Henny, Zhao, Jian-Ping, Strouf, Haley, Heidenreich, Matthias, Swiech, Lukasz, Deverman, Benjamin E., Gradinaru, Viviana, Zhang, Feng, Constantine-Paton, Martha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644554/
https://www.ncbi.nlm.nih.gov/pubmed/37957716
http://dx.doi.org/10.1186/s12915-023-01714-y

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