Genetically predicted triglycerides mediate the relationship between type 2 diabetes Mellitus and intervertebral disc degeneration

BACKGROUND: To validate the causal relationship between type 2 diabetes mellitus (T2DM) and intervertebral disc degeneration (IVDD) and to identify and quantify the role of triglycerides (TGs) as potential mediators. METHODS: A two-sample Mendelian randomization (MR) analyses of T2DM (61,714 cases a...

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Detalles Bibliográficos
Autores principales: Chen, Ding-Qiang, Xu, Wen-Bin, Chen, Xin, Xiao, Ke-Yi, Que, Zhi-Qiang, Sun, Nai-Kun, Feng, Jin-Yi, Rui, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644578/
https://www.ncbi.nlm.nih.gov/pubmed/37964277
http://dx.doi.org/10.1186/s12944-023-01963-4

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