Cargando…

Sex-based differences in natural killer T cell-mediated protection against diet-induced steatohepatitis in Balb/c mice

BACKGROUND: Metabolic dysfunction-associated steatotic liver disease (MASLD) is prevalent in Western countries, evolving into metabolic dysfunction-associated steatohepatitis (MASH) with a sexual dimorphism. Fertile women exhibit lower MASLD risk than men, which diminishes post-menopause. While NKT-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cuño-Gómiz, Carlos, de Gregorio, Estefanía, Tutusaus, Anna, Rider, Patricia, Andrés-Sánchez, Nuria, Colell, Anna, Morales, Albert, Marí, Montserrat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644614/ https://www.ncbi.nlm.nih.gov/pubmed/37964320 http://dx.doi.org/10.1186/s13293-023-00569-w

Ejemplares similares

Hepatocellular Carcinoma: Molecular Pathogenesis and Therapeutic Advances
por: Cucarull, Blanca, et al.
Publicado: (2022)

A Functional Role of GAS6/TAM in Nonalcoholic Steatohepatitis Progression Implicates AXL as Therapeutic Target
por: Tutusaus, Anna, et al.
Publicado: (2019)

Cysteine cathepsins control hepatic NF-κB-dependent inflammation via sirtuin-1 regulation
por: de Mingo, Álvaro, et al.
Publicado: (2016)

Mitochondrial Glutathione: Recent Insights and Role in Disease
por: Marí, Montserrat, et al.
Publicado: (2020)

Relevance of SIRT1-NF-κB Axis as Therapeutic Target to Ameliorate Inflammation in Liver Disease
por: de Gregorio, Estefanía, et al.
Publicado: (2020)

Antioxidants Threaten Multikinase Inhibitor Efficacy against Liver Cancer by Blocking Mitochondrial Reactive Oxygen Species
por: Cucarull, Blanca, et al.
Publicado: (2021)

Differential Role of Cathepsins S and B In Hepatic APC-Mediated NKT Cell Activation and Cytokine Secretion
por: de Mingo Pulido, Álvaro, et al.
Publicado: (2018)

Targeting glucosylceramide synthase upregulation reverts sorafenib resistance in experimental hepatocellular carcinoma
por: Stefanovic, Milica, et al.
Publicado: (2016)

Regorafenib Alteration of the BCL-xL/MCL-1 Ratio Provides a Therapeutic Opportunity for BH3-Mimetics in Hepatocellular Carcinoma Models
por: Cucarull, Blanca, et al.
Publicado: (2020)

Mitochondrial Oxidative and Nitrosative Stress as a Therapeutic Target in Diseases
por: Marí, Montserrat, et al.
Publicado: (2021)

Antiapoptotic BCL-2 proteins determine sorafenib/regorafenib resistance and BH3-mimetic efficacy in hepatocellular carcinoma
por: Tutusaus, Anna, et al.
Publicado: (2018)

Mitochondrial cholesterol accumulation in alcoholic liver disease: Role of ASMase and endoplasmic reticulum stress
por: Marí, Montserrat, et al.
Publicado: (2014)

Recent Insights into the Mitochondrial Role in Autophagy and Its Regulation by Oxidative Stress
por: Roca-Agujetas, Vicente, et al.
Publicado: (2019)

The Impact of High-Fat Diet and Restrictive Feeding on Natural Killer Cells in Obese-Resistant BALB/c Mice
por: Spielmann, Julia, et al.
Publicado: (2021)

The Role of Natural Killer Cells in Nonalcoholic Steatohepatitis: An Ongoing Debate
por: Jiang, Xiaojun, et al.
Publicado: (2021)

Role of Vitamin K-Dependent Factors Protein S and GAS6 and TAM Receptors in SARS-CoV-2 Infection and COVID-19-Associated Immunothrombosis
por: Tutusaus, Anna, et al.
Publicado: (2020)

Oxidative inactivation of amyloid beta-degrading proteases by cholesterol-enhanced mitochondrial stress
por: de Dios, Cristina, et al.
Publicado: (2019)

A comparative study on roles of natural killer T cells in two diet-induced non-alcoholic steatohepatitis-related fibrosis in mice
por: Zheng, Shumei, et al.
Publicado: (2022)

Inflammasome activation under high cholesterol load triggers a protective microglial phenotype while promoting neuronal pyroptosis
por: de Dios, Cristina, et al.
Publicado: (2023)

Hepatic natural killer T‐cell and CD8+ T‐cell signatures in mice with nonalcoholic steatohepatitis
por: Bhattacharjee, Jashdeep, et al.
Publicado: (2017)

Cholesterol alters mitophagy by impairing optineurin recruitment and lysosomal clearance in Alzheimer’s disease
por: Roca-Agujetas, Vicente, et al.
Publicado: (2021)

Activated Natural Killer Cell Promotes Nonalcoholic Steatohepatitis Through Mediating JAK/STAT Pathway
por: Wang, Feixue, et al.
Publicado: (2021)

Cholesterol impairs autophagy-mediated clearance of amyloid beta while promoting its secretion
por: Barbero-Camps, Elisabet, et al.
Publicado: (2018)

Overexpression of Hepcidin Alleviates Steatohepatitis and Fibrosis in a Diet-induced Nonalcoholic Steatohepatitis
por: Chen, Hui, et al.
Publicado: (2022)

Akkermansia muciniphila suppressing nonalcoholic steatohepatitis associated tumorigenesis through CXCR6(+) natural killer T cells
por: Li, Tao, et al.
Publicado: (2022)

Corrigendum: Akkermansia muciniphila suppressing nonalcoholic steatohepatitis associated tumorigenesis through CXCR6(+) natural killer T cells
por: Li, Tao, et al.
Publicado: (2023)

Ketogenic, Hypocaloric Diet Improves Nonalcoholic Steatohepatitis
por: Belopolsky, Yuliya, et al.
Publicado: (2020)

Lycopene Prevents Development of Steatohepatitis in Experimental Nonalcoholic Steatohepatitis Model Induced by High-Fat Diet
por: Bahcecioglu, Ibrahim Halil, et al.
Publicado: (2010)

Functional Inhibition of Natural Killer Cells in a BALB/c Mouse Model of Liver Fibrosis Induced by Schistosoma japonicum Infection
por: Hu, Yuan, et al.
Publicado: (2020)

High-fat diet decreases activity of the oxidative phosphorylation complexes and causes nonalcoholic steatohepatitis in mice
por: García-Ruiz, Inmaculada, et al.
Publicado: (2014)

Mouse Models of Diet-Induced Nonalcoholic Steatohepatitis Reproduce the Heterogeneity of the Human Disease
por: Machado, Mariana Verdelho, et al.
Publicado: (2015)

Angiogenin Secretion From Hepatoma Cells Activates Hepatic Stellate Cells To Amplify A Self-Sustained Cycle Promoting Liver Cancer
por: Bárcena, Cristina, et al.
Publicado: (2015)

Sex differences in variability across timescales in BALB/c mice
por: Smarr, Benjamin L., et al.
Publicado: (2017)

A novel diet‐induced murine model of steatohepatitis with fibrosis for screening and evaluation of drug candidates for nonalcoholic steatohepatitis
por: Ejima, Chieko, et al.
Publicado: (2016)

Correction: Mouse Models of Diet-Induced Nonalcoholic Steatohepatitis Reproduce the Heterogeneity of the Human Disease
por: Machado, Mariana Verdelho, et al.
Publicado: (2015)

Visibilizar la discapacidad : hacia un modelo de ciudadanía inclusiva /
por: Gomiz Pascual, María del Pilar
Publicado: (2017)

Prolonged cenicriviroc therapy reduces hepatic fibrosis despite steatohepatitis in a diet‐induced mouse model of nonalcoholic steatohepatitis
por: Kruger, Annie J., et al.
Publicado: (2018)

The Influence of Different Fat Sources on Steatohepatitis and Fibrosis Development in the Western Diet Mouse Model of Non-alcoholic Steatohepatitis (NASH)
por: Drescher, Hannah K., et al.
Publicado: (2019)

Caspase 1-mediated regulation of fibrogenesis in diet-induced steatohepatitis
por: Dixon, Laura, et al.
Publicado: (2012)

Is Western Diet-Induced Nonalcoholic Steatohepatitis in Ldlr(-/-) Mice Reversible?
por: Lytle, Kelli A., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_pdrnonk4thjmdjpgnl98ci18ir