Tau seed amplification assay reveals relationship between seeding and pathological forms of tau in Alzheimer’s disease brain

Tau seed amplification assays (SAAs) directly measure the seeding activity of tau and would therefore be ideal biomarkers for clinical trials targeting seeding-competent tau in Alzheimer’s disease (AD). However, the precise relationship between tau seeding measured by SAA and the levels of pathologi...

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Detalles Bibliográficos
Autores principales: Frey, Bryan, Holzinger, David, Taylor, Keenan, Ehrnhoefer, Dagmar E., Striebinger, Andreas, Biesinger, Sandra, Gasparini, Laura, O’Neill, Michael J., Wegner, Florian, Barghorn, Stefan, Höglinger, Günter U., Heym, Roland G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644662/
https://www.ncbi.nlm.nih.gov/pubmed/37964332
http://dx.doi.org/10.1186/s40478-023-01676-w

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