Discovery of inhibitors of protein tyrosine phosphatase 1B contained in a natural products library from Mexican medicinal plants and fungi using a combination of enzymatic and in silico methods**

This work aimed to discover protein tyrosine phosphatase 1B (PTP1B) inhibitors from a small molecule library of natural products (NPs) derived from selected Mexican medicinal plants and fungi to find new hits for developing antidiabetic drugs. The products showing similar IC(50) values to ursolic ac...

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Detalles Bibliográficos
Autores principales: Díaz-Rojas, Miriam, González-Andrade, Martin, Aguayo-Ortiz, Rodrigo, Rodríguez-Sotres, Rogelio, Pérez-Vásquez, Araceli, Madariaga-Mazón, Abraham, Mata, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644722/
https://www.ncbi.nlm.nih.gov/pubmed/38027024
http://dx.doi.org/10.3389/fphar.2023.1281045

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