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GnRH-immunocastration: an alternative method for male animal surgical castration
Castration of male animals is intended to produce high-enhance quality of animal meat, prevent unpleasant taste, reduce aggressive behavior, and manage overbreeding. Over the years, Tranditional methods of mechanical and surgical castration have been employed over the years, but they fall short of m...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644813/ https://www.ncbi.nlm.nih.gov/pubmed/38026623 http://dx.doi.org/10.3389/fvets.2023.1248879 |
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author | Wang, Chun Yang, Cuiting Zeng, Yutian Zhang, Ming |
author_facet | Wang, Chun Yang, Cuiting Zeng, Yutian Zhang, Ming |
author_sort | Wang, Chun |
collection | PubMed |
description | Castration of male animals is intended to produce high-enhance quality of animal meat, prevent unpleasant taste, reduce aggressive behavior, and manage overbreeding. Over the years, Tranditional methods of mechanical and surgical castration have been employed over the years, but they fall short of meeting animal welfare requirements due to the associated risk of infection, pain, and stress. Immunocastration, specifically Gonadotropin-releasing hormone (GnRH)-immunocastration, targeting the hypothalamic–pituitary-testis (HPT) axis, has emerged as an animal-friendly alternative to surgical castration, effectively addressing these issues. This review seeks to systematically summarize the principles, development, current applications and challenges of GnRH-immunocastration, offering insights into its role in promoting animal welfare. |
format | Online Article Text |
id | pubmed-10644813 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-106448132023-01-01 GnRH-immunocastration: an alternative method for male animal surgical castration Wang, Chun Yang, Cuiting Zeng, Yutian Zhang, Ming Front Vet Sci Veterinary Science Castration of male animals is intended to produce high-enhance quality of animal meat, prevent unpleasant taste, reduce aggressive behavior, and manage overbreeding. Over the years, Tranditional methods of mechanical and surgical castration have been employed over the years, but they fall short of meeting animal welfare requirements due to the associated risk of infection, pain, and stress. Immunocastration, specifically Gonadotropin-releasing hormone (GnRH)-immunocastration, targeting the hypothalamic–pituitary-testis (HPT) axis, has emerged as an animal-friendly alternative to surgical castration, effectively addressing these issues. This review seeks to systematically summarize the principles, development, current applications and challenges of GnRH-immunocastration, offering insights into its role in promoting animal welfare. Frontiers Media S.A. 2023-10-31 /pmc/articles/PMC10644813/ /pubmed/38026623 http://dx.doi.org/10.3389/fvets.2023.1248879 Text en Copyright © 2023 Wang, Yang, Zeng and Zhang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Veterinary Science Wang, Chun Yang, Cuiting Zeng, Yutian Zhang, Ming GnRH-immunocastration: an alternative method for male animal surgical castration |
title | GnRH-immunocastration: an alternative method for male animal surgical castration |
title_full | GnRH-immunocastration: an alternative method for male animal surgical castration |
title_fullStr | GnRH-immunocastration: an alternative method for male animal surgical castration |
title_full_unstemmed | GnRH-immunocastration: an alternative method for male animal surgical castration |
title_short | GnRH-immunocastration: an alternative method for male animal surgical castration |
title_sort | gnrh-immunocastration: an alternative method for male animal surgical castration |
topic | Veterinary Science |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644813/ https://www.ncbi.nlm.nih.gov/pubmed/38026623 http://dx.doi.org/10.3389/fvets.2023.1248879 |
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