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Rapid Diagnosis of Hemophagocytic Lymphohistiocytosis Triggered by Disseminated BCG Infection in Infants With Severe Combined Immunodeficiency: Case Report

Hemophagocytic lymphohistiocytosis triggered by disseminated Bacillus Calmette-Guerin infection is rare. Targeted next-generation sequencing for tuberculosis can rapidly identify different strains of Mycobacterium tuberculosis complex as well as drug resistance genes. Herein we report 2 cases of hem...

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Autores principales: Zou, Ting-Ting, Liao, Qiong, Liu, Yang, Guo, Qin, Zhu, Yu, Wan, Chao-min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644825/
https://www.ncbi.nlm.nih.gov/pubmed/38023550
http://dx.doi.org/10.1093/ofid/ofad548
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author Zou, Ting-Ting
Liao, Qiong
Liu, Yang
Guo, Qin
Zhu, Yu
Wan, Chao-min
author_facet Zou, Ting-Ting
Liao, Qiong
Liu, Yang
Guo, Qin
Zhu, Yu
Wan, Chao-min
author_sort Zou, Ting-Ting
collection PubMed
description Hemophagocytic lymphohistiocytosis triggered by disseminated Bacillus Calmette-Guerin infection is rare. Targeted next-generation sequencing for tuberculosis can rapidly identify different strains of Mycobacterium tuberculosis complex as well as drug resistance genes. Herein we report 2 cases of hemophagocytic lymphohistiocytosis in whom targeted next-generation sequencing rapidly identified Bacillus Calmette-Guerin as the infectious trigger.
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spelling pubmed-106448252023-11-02 Rapid Diagnosis of Hemophagocytic Lymphohistiocytosis Triggered by Disseminated BCG Infection in Infants With Severe Combined Immunodeficiency: Case Report Zou, Ting-Ting Liao, Qiong Liu, Yang Guo, Qin Zhu, Yu Wan, Chao-min Open Forum Infect Dis Brief Report Hemophagocytic lymphohistiocytosis triggered by disseminated Bacillus Calmette-Guerin infection is rare. Targeted next-generation sequencing for tuberculosis can rapidly identify different strains of Mycobacterium tuberculosis complex as well as drug resistance genes. Herein we report 2 cases of hemophagocytic lymphohistiocytosis in whom targeted next-generation sequencing rapidly identified Bacillus Calmette-Guerin as the infectious trigger. Oxford University Press 2023-11-02 /pmc/articles/PMC10644825/ /pubmed/38023550 http://dx.doi.org/10.1093/ofid/ofad548 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Zou, Ting-Ting
Liao, Qiong
Liu, Yang
Guo, Qin
Zhu, Yu
Wan, Chao-min
Rapid Diagnosis of Hemophagocytic Lymphohistiocytosis Triggered by Disseminated BCG Infection in Infants With Severe Combined Immunodeficiency: Case Report
title Rapid Diagnosis of Hemophagocytic Lymphohistiocytosis Triggered by Disseminated BCG Infection in Infants With Severe Combined Immunodeficiency: Case Report
title_full Rapid Diagnosis of Hemophagocytic Lymphohistiocytosis Triggered by Disseminated BCG Infection in Infants With Severe Combined Immunodeficiency: Case Report
title_fullStr Rapid Diagnosis of Hemophagocytic Lymphohistiocytosis Triggered by Disseminated BCG Infection in Infants With Severe Combined Immunodeficiency: Case Report
title_full_unstemmed Rapid Diagnosis of Hemophagocytic Lymphohistiocytosis Triggered by Disseminated BCG Infection in Infants With Severe Combined Immunodeficiency: Case Report
title_short Rapid Diagnosis of Hemophagocytic Lymphohistiocytosis Triggered by Disseminated BCG Infection in Infants With Severe Combined Immunodeficiency: Case Report
title_sort rapid diagnosis of hemophagocytic lymphohistiocytosis triggered by disseminated bcg infection in infants with severe combined immunodeficiency: case report
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644825/
https://www.ncbi.nlm.nih.gov/pubmed/38023550
http://dx.doi.org/10.1093/ofid/ofad548
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