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Rapid Diagnosis of Hemophagocytic Lymphohistiocytosis Triggered by Disseminated BCG Infection in Infants With Severe Combined Immunodeficiency: Case Report
Hemophagocytic lymphohistiocytosis triggered by disseminated Bacillus Calmette-Guerin infection is rare. Targeted next-generation sequencing for tuberculosis can rapidly identify different strains of Mycobacterium tuberculosis complex as well as drug resistance genes. Herein we report 2 cases of hem...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644825/ https://www.ncbi.nlm.nih.gov/pubmed/38023550 http://dx.doi.org/10.1093/ofid/ofad548 |
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author | Zou, Ting-Ting Liao, Qiong Liu, Yang Guo, Qin Zhu, Yu Wan, Chao-min |
author_facet | Zou, Ting-Ting Liao, Qiong Liu, Yang Guo, Qin Zhu, Yu Wan, Chao-min |
author_sort | Zou, Ting-Ting |
collection | PubMed |
description | Hemophagocytic lymphohistiocytosis triggered by disseminated Bacillus Calmette-Guerin infection is rare. Targeted next-generation sequencing for tuberculosis can rapidly identify different strains of Mycobacterium tuberculosis complex as well as drug resistance genes. Herein we report 2 cases of hemophagocytic lymphohistiocytosis in whom targeted next-generation sequencing rapidly identified Bacillus Calmette-Guerin as the infectious trigger. |
format | Online Article Text |
id | pubmed-10644825 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-106448252023-11-02 Rapid Diagnosis of Hemophagocytic Lymphohistiocytosis Triggered by Disseminated BCG Infection in Infants With Severe Combined Immunodeficiency: Case Report Zou, Ting-Ting Liao, Qiong Liu, Yang Guo, Qin Zhu, Yu Wan, Chao-min Open Forum Infect Dis Brief Report Hemophagocytic lymphohistiocytosis triggered by disseminated Bacillus Calmette-Guerin infection is rare. Targeted next-generation sequencing for tuberculosis can rapidly identify different strains of Mycobacterium tuberculosis complex as well as drug resistance genes. Herein we report 2 cases of hemophagocytic lymphohistiocytosis in whom targeted next-generation sequencing rapidly identified Bacillus Calmette-Guerin as the infectious trigger. Oxford University Press 2023-11-02 /pmc/articles/PMC10644825/ /pubmed/38023550 http://dx.doi.org/10.1093/ofid/ofad548 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Brief Report Zou, Ting-Ting Liao, Qiong Liu, Yang Guo, Qin Zhu, Yu Wan, Chao-min Rapid Diagnosis of Hemophagocytic Lymphohistiocytosis Triggered by Disseminated BCG Infection in Infants With Severe Combined Immunodeficiency: Case Report |
title | Rapid Diagnosis of Hemophagocytic Lymphohistiocytosis Triggered by Disseminated BCG Infection in Infants With Severe Combined Immunodeficiency: Case Report |
title_full | Rapid Diagnosis of Hemophagocytic Lymphohistiocytosis Triggered by Disseminated BCG Infection in Infants With Severe Combined Immunodeficiency: Case Report |
title_fullStr | Rapid Diagnosis of Hemophagocytic Lymphohistiocytosis Triggered by Disseminated BCG Infection in Infants With Severe Combined Immunodeficiency: Case Report |
title_full_unstemmed | Rapid Diagnosis of Hemophagocytic Lymphohistiocytosis Triggered by Disseminated BCG Infection in Infants With Severe Combined Immunodeficiency: Case Report |
title_short | Rapid Diagnosis of Hemophagocytic Lymphohistiocytosis Triggered by Disseminated BCG Infection in Infants With Severe Combined Immunodeficiency: Case Report |
title_sort | rapid diagnosis of hemophagocytic lymphohistiocytosis triggered by disseminated bcg infection in infants with severe combined immunodeficiency: case report |
topic | Brief Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644825/ https://www.ncbi.nlm.nih.gov/pubmed/38023550 http://dx.doi.org/10.1093/ofid/ofad548 |
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