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Magnetic Microrobots Fabricated by Photopolymerization and Assembly

Magnetic soft microrobots have great potential to access narrow spaces and conduct multiple tasks in the biomedical field. Until now, drug delivery, microsurgery, disease diagnosis, and dredging the blocked blood vessel have been realized by magnetic soft microrobots in vivo or in vitro. However, as...

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Detalles Bibliográficos
Autores principales: Liang, Xiyue, Zhao, Yue, Liu, Dan, Deng, Yan, Arai, Tatsuo, Kojima, Masaru, Liu, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAAS 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644835/
https://www.ncbi.nlm.nih.gov/pubmed/38026540
http://dx.doi.org/10.34133/cbsystems.0060
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author Liang, Xiyue
Zhao, Yue
Liu, Dan
Deng, Yan
Arai, Tatsuo
Kojima, Masaru
Liu, Xiaoming
author_facet Liang, Xiyue
Zhao, Yue
Liu, Dan
Deng, Yan
Arai, Tatsuo
Kojima, Masaru
Liu, Xiaoming
author_sort Liang, Xiyue
collection PubMed
description Magnetic soft microrobots have great potential to access narrow spaces and conduct multiple tasks in the biomedical field. Until now, drug delivery, microsurgery, disease diagnosis, and dredging the blocked blood vessel have been realized by magnetic soft microrobots in vivo or in vitro. However, as the tasks become more and more complex, more functional units have been embedded in the body of the developed magnetic microrobots. These magnetic soft microrobots with complex designed geometries, mechanisms, and magnetic orientation are now greatly challenging the fabrication of the magnetic microrobots. In this paper, we propose a new method combining photopolymerization and assembly for the fabrication of magnetic soft microrobots. Utilizing the micro-hand assembly system, magnetic modules with different shapes and materials are firstly arrayed with precise position and orientation control. Then, the developed photopolymerization system is employed to fix and link these modules with soft materials. Based on the proposed fabrication method, 3 kinds of soft magnetic microrobots were fabricated, and the fundamental locomotion was presented. We believe that the presented fabrication strategy could help accelerate the clinical application of magnetic microrobots.
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spelling pubmed-106448352023-11-14 Magnetic Microrobots Fabricated by Photopolymerization and Assembly Liang, Xiyue Zhao, Yue Liu, Dan Deng, Yan Arai, Tatsuo Kojima, Masaru Liu, Xiaoming Cyborg Bionic Syst Research Article Magnetic soft microrobots have great potential to access narrow spaces and conduct multiple tasks in the biomedical field. Until now, drug delivery, microsurgery, disease diagnosis, and dredging the blocked blood vessel have been realized by magnetic soft microrobots in vivo or in vitro. However, as the tasks become more and more complex, more functional units have been embedded in the body of the developed magnetic microrobots. These magnetic soft microrobots with complex designed geometries, mechanisms, and magnetic orientation are now greatly challenging the fabrication of the magnetic microrobots. In this paper, we propose a new method combining photopolymerization and assembly for the fabrication of magnetic soft microrobots. Utilizing the micro-hand assembly system, magnetic modules with different shapes and materials are firstly arrayed with precise position and orientation control. Then, the developed photopolymerization system is employed to fix and link these modules with soft materials. Based on the proposed fabrication method, 3 kinds of soft magnetic microrobots were fabricated, and the fundamental locomotion was presented. We believe that the presented fabrication strategy could help accelerate the clinical application of magnetic microrobots. AAAS 2023-11-14 /pmc/articles/PMC10644835/ /pubmed/38026540 http://dx.doi.org/10.34133/cbsystems.0060 Text en Copyright © 2023 Xiyue Liang et al. https://creativecommons.org/licenses/by/4.0/Exclusive licensee Beijing Institute of Technology Press. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY 4.0) (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Research Article
Liang, Xiyue
Zhao, Yue
Liu, Dan
Deng, Yan
Arai, Tatsuo
Kojima, Masaru
Liu, Xiaoming
Magnetic Microrobots Fabricated by Photopolymerization and Assembly
title Magnetic Microrobots Fabricated by Photopolymerization and Assembly
title_full Magnetic Microrobots Fabricated by Photopolymerization and Assembly
title_fullStr Magnetic Microrobots Fabricated by Photopolymerization and Assembly
title_full_unstemmed Magnetic Microrobots Fabricated by Photopolymerization and Assembly
title_short Magnetic Microrobots Fabricated by Photopolymerization and Assembly
title_sort magnetic microrobots fabricated by photopolymerization and assembly
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644835/
https://www.ncbi.nlm.nih.gov/pubmed/38026540
http://dx.doi.org/10.34133/cbsystems.0060
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