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Roux-en-Y Gastric Bypass Improves Insulin Sensitivity in Obese Rats with Type 2 Diabetes Mellitus by Regulating the Grin3a/AMPK Signal Axis in Hypothalamic Arcuate Nucleus

OBJECTIVE: The objective of this study was to explore the effects and related mechanisms of Roux-en-Y gastric bypass (RYGB) on insulin sensitivity in obese rats with type 2 diabetes mellitus (T2DM). METHODS: The obese T2DM rat model was constructed by feeding a high-fat diet and injecting streptozot...

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Detalles Bibliográficos
Autores principales: Zhang, Li-Hai, Wang, Jiao, Tan, Bai-Hong, Yin, Yan-Bin, Kang, Yu-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644885/
https://www.ncbi.nlm.nih.gov/pubmed/38028990
http://dx.doi.org/10.2147/DMSO.S430445

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