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Targeting amyotrophic lateral sclerosis by neutralizing seeding-competent TDP-43 in CSF
In amyotrophic lateral sclerosis, a disease driven by abnormal transactive response DNA-binding protein of 43 kDa aggregation, CSF may contain pathological species of transactive response DNA-binding protein of 43 kDa contributing to the propagation of pathology and neuronal toxicity. These species,...
Autores principales: | Audrain, Mickael, Egesipe, Anne-Laure, Tentillier, Noémie, Font, Laure, Ratnam, Monisha, Mottier, Lorene, Clavel, Mathieu, Le Roux-Bourdieu, Morgan, Fenyi, Alexis, Ollier, Romain, Chevalier, Elodie, Guilhot, Florence, Fuchs, Aline, Piorkowska, Kasia, Carlyle, Becky, Arnold, Steven E, Berry, James D, Luthi-Carter, Ruth, Adolfsson, Oskar, Pfeifer, Andrea, Kosco-Vilbois, Marie, Seredenina, Tamara, Afroz, Tariq |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644982/ https://www.ncbi.nlm.nih.gov/pubmed/38025276 http://dx.doi.org/10.1093/braincomms/fcad306 |
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