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Colonic stenting in acute malignant large bowel obstruction: audit of efficacy and safety in a Singapore tertiary referral centre

INTRODUCTION: Acute malignant large bowel obstruction (MBO) occurs in 8%–15% of colorectal cancer patients. Self-expandable metal stents (SEMS) have progressed from a palliative modality to use as bridge to surgery (BTS). We aimed to assess the safety and efficacy of SEMS for MBO in our institution....

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Autores principales: Li, James Weiquan, Ngu, James Chi-Yong, Lim, Kok Ren, Tay, Shu Wen, Jiang, Bochao, Wijaya, Ramesh, Yusof, Sulaiman, Ong, Calvin Jianming, Kwek, Andrew Boon Eu, Ang, Tiing Leong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645007/
https://www.ncbi.nlm.nih.gov/pubmed/34600451
http://dx.doi.org/10.11622/smedj.2021127
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author Li, James Weiquan
Ngu, James Chi-Yong
Lim, Kok Ren
Tay, Shu Wen
Jiang, Bochao
Wijaya, Ramesh
Yusof, Sulaiman
Ong, Calvin Jianming
Kwek, Andrew Boon Eu
Ang, Tiing Leong
author_facet Li, James Weiquan
Ngu, James Chi-Yong
Lim, Kok Ren
Tay, Shu Wen
Jiang, Bochao
Wijaya, Ramesh
Yusof, Sulaiman
Ong, Calvin Jianming
Kwek, Andrew Boon Eu
Ang, Tiing Leong
author_sort Li, James Weiquan
collection PubMed
description INTRODUCTION: Acute malignant large bowel obstruction (MBO) occurs in 8%–15% of colorectal cancer patients. Self-expandable metal stents (SEMS) have progressed from a palliative modality to use as bridge to surgery (BTS). We aimed to assess the safety and efficacy of SEMS for MBO in our institution. METHODS: The data of patients undergoing SEMS insertion for MBO were reviewed. Technical success was defined as successful SEMS deployment across tumour without complications. Clinical success was defined as colonic decompression without requiring further surgical intervention. Rates of complications, median time to surgery, types of surgery and rates of recurrence were studied. RESULTS: Seventy-nine patients underwent emergent SEMS placement from September 2013 to February 2020. Their mean age was 68.8 ± 13.8 years and 43 (54%) patients were male. Mean tumour length was 4.2 cm ± 2.2 cm; 89.9% of malignant strictures were located distal to the splenic flexure. Technical and clinical success was 94.9% and 98.7%, respectively. Perforation occurred in 5.1% of patients, with none having stent migration or bleeding. Fifty (63.3%) patients underwent SEMS insertion as BTS. Median time to surgery was 20 (range 6–57) days. Most (82%) patients underwent minimally invasive surgery. Primary anastomosis rate was 98%. Thirty-nine patients had follow-up beyond 1-year posttreatment (median 34 months). Local recurrence and distant metastasis were observed in 4 (10.3%) and 5 (12.8%) patients, respectively. CONCLUSION: Insertion of SEMS for acute MBO has high success rates and a good safety profile. Most patients in this audit underwent minimally invasive surgery and primary anastomosis after successful BTS.
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spelling pubmed-106450072023-11-15 Colonic stenting in acute malignant large bowel obstruction: audit of efficacy and safety in a Singapore tertiary referral centre Li, James Weiquan Ngu, James Chi-Yong Lim, Kok Ren Tay, Shu Wen Jiang, Bochao Wijaya, Ramesh Yusof, Sulaiman Ong, Calvin Jianming Kwek, Andrew Boon Eu Ang, Tiing Leong Singapore Med J Original Article INTRODUCTION: Acute malignant large bowel obstruction (MBO) occurs in 8%–15% of colorectal cancer patients. Self-expandable metal stents (SEMS) have progressed from a palliative modality to use as bridge to surgery (BTS). We aimed to assess the safety and efficacy of SEMS for MBO in our institution. METHODS: The data of patients undergoing SEMS insertion for MBO were reviewed. Technical success was defined as successful SEMS deployment across tumour without complications. Clinical success was defined as colonic decompression without requiring further surgical intervention. Rates of complications, median time to surgery, types of surgery and rates of recurrence were studied. RESULTS: Seventy-nine patients underwent emergent SEMS placement from September 2013 to February 2020. Their mean age was 68.8 ± 13.8 years and 43 (54%) patients were male. Mean tumour length was 4.2 cm ± 2.2 cm; 89.9% of malignant strictures were located distal to the splenic flexure. Technical and clinical success was 94.9% and 98.7%, respectively. Perforation occurred in 5.1% of patients, with none having stent migration or bleeding. Fifty (63.3%) patients underwent SEMS insertion as BTS. Median time to surgery was 20 (range 6–57) days. Most (82%) patients underwent minimally invasive surgery. Primary anastomosis rate was 98%. Thirty-nine patients had follow-up beyond 1-year posttreatment (median 34 months). Local recurrence and distant metastasis were observed in 4 (10.3%) and 5 (12.8%) patients, respectively. CONCLUSION: Insertion of SEMS for acute MBO has high success rates and a good safety profile. Most patients in this audit underwent minimally invasive surgery and primary anastomosis after successful BTS. Wolters Kluwer - Medknow 2021-10-03 /pmc/articles/PMC10645007/ /pubmed/34600451 http://dx.doi.org/10.11622/smedj.2021127 Text en Copyright: © 2023 Singapore Medical Journal https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Li, James Weiquan
Ngu, James Chi-Yong
Lim, Kok Ren
Tay, Shu Wen
Jiang, Bochao
Wijaya, Ramesh
Yusof, Sulaiman
Ong, Calvin Jianming
Kwek, Andrew Boon Eu
Ang, Tiing Leong
Colonic stenting in acute malignant large bowel obstruction: audit of efficacy and safety in a Singapore tertiary referral centre
title Colonic stenting in acute malignant large bowel obstruction: audit of efficacy and safety in a Singapore tertiary referral centre
title_full Colonic stenting in acute malignant large bowel obstruction: audit of efficacy and safety in a Singapore tertiary referral centre
title_fullStr Colonic stenting in acute malignant large bowel obstruction: audit of efficacy and safety in a Singapore tertiary referral centre
title_full_unstemmed Colonic stenting in acute malignant large bowel obstruction: audit of efficacy and safety in a Singapore tertiary referral centre
title_short Colonic stenting in acute malignant large bowel obstruction: audit of efficacy and safety in a Singapore tertiary referral centre
title_sort colonic stenting in acute malignant large bowel obstruction: audit of efficacy and safety in a singapore tertiary referral centre
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645007/
https://www.ncbi.nlm.nih.gov/pubmed/34600451
http://dx.doi.org/10.11622/smedj.2021127
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