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Association of CYP3A5()3, CYP3A4()18 & CYP2B6(*)6 polymorphisms with imatinib treatment outcome in Azerbaijani chronic myeloid leukaemia patients

BACKGROUND & OBJECTIVES: Imatinib mesylate (IM) is a reliable first line treatment for chronic myeloid leukaemia (CML). Nevertheless, despite promising results, a considerable proportion of patients develop resistance to the drug. Cytochrome P450 (CYP) enzymes play a crucial role in IM metabolis...

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Detalles Bibliográficos
Autores principales:	Asadov, Chingiz, Karimova, Nigar, Hasanova, Aypara, Bayramov, Bayram, Shirinova, Aytan, Alimirzoyeva, Zohra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer - Medknow 2023
Materias:	Practice: Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645035/ https://www.ncbi.nlm.nih.gov/pubmed/37706370 http://dx.doi.org/10.4103/ijmr.ijmr_1103_22

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