Plasma Nitric Oxide Consumption Is Elevated and Associated With Adverse Outcomes in Critically Ill Patients

OBJECTIVES: Impaired nitric oxide (NO) bioavailability may contribute to microvascular dysfunction in sepsis. Excessive plasma NO consumption has been attributed to scavenging by circulating cell-free hemoglobin. This may be a mechanism for NO deficiency in sepsis and critical illness. We hypothesiz...

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Detalles Bibliográficos
Autores principales: Dony, Christina A., Illipparambil, Lijo C., Maeda, Tetsuro, Mroczek, Susan K., Rovitelli, Amy, Wexler, Orren, Malnoske, Michelle, Bice, Tristan, Fe, Alex Z., Storms, Casey R., Zhang, Jimmy, Schultz, Rebecca D., Pietropaoli, Anthony P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Clinical Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645105/
https://www.ncbi.nlm.nih.gov/pubmed/37607081
http://dx.doi.org/10.1097/CCM.0000000000006006

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