Cargando…
Regulation of the heterochromatin spreading reaction by trans-acting factors
Heterochromatin is a gene-repressive protein–nucleic acid ultrastructure that is initially nucleated by DNA sequences. However, following nucleation, heterochromatin can then propagate along the chromatin template in a sequence-independent manner in a reaction termed spreading. At the heart of this...
Autores principales: | Hamali, Bulut, Amine, Ahmed A. A., Al-Sady, Bassem |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645111/ https://www.ncbi.nlm.nih.gov/pubmed/37935357 http://dx.doi.org/10.1098/rsob.230271 |
Ejemplares similares
-
Local chromatin context regulates the genetic requirements of the heterochromatin spreading reaction
por: Greenstein, R. A., et al.
Publicado: (2022) -
Intrinsic Toxicity of Unchecked Heterochromatin Spread Is Suppressed by Redundant Chromatin Boundary Functions in Schizosacchromyces pombe
por: Garcia, Jennifer F., et al.
Publicado: (2015) -
A dual, catalytic role for the fission yeast Ccr4-Not complex in gene silencing and heterochromatin spreading
por: Challal, Drice, et al.
Publicado: (2023) -
Noncoding RNA-nucleated heterochromatin spreading is intrinsically labile and requires accessory elements for epigenetic stability
por: Greenstein, R A, et al.
Publicado: (2018) -
The histone chaperone FACT facilitates heterochromatin spreading by regulating histone turnover and H3K9 methylation states
por: Murawska, Magdalena, et al.
Publicado: (2021)