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Effect of pulmonary embolism location on electrocardiological parameters

OBJECTIVE: Pulmonary thromboembolism is a disease with high morbidity and mortality. Various changes occur on the electrocardiogram secondary to pulmonary thromboembolism. The objective of this study was to investigate variations in QT dispersion, Tpeak-Tend duration, and Tpeak-Tend/QT ratio in rela...

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Autores principales: Günay, Serkan, Şancı, Emre, Sarı, Ahmet Emir, Gümüş, Semiha Aksoy, Özen, Deniz Kaptan, Halhallı, Hüseyin Cahit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Médica Brasileira 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645181/
https://www.ncbi.nlm.nih.gov/pubmed/37971127
http://dx.doi.org/10.1590/1806-9282.20230733
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author Günay, Serkan
Şancı, Emre
Sarı, Ahmet Emir
Gümüş, Semiha Aksoy
Özen, Deniz Kaptan
Halhallı, Hüseyin Cahit
author_facet Günay, Serkan
Şancı, Emre
Sarı, Ahmet Emir
Gümüş, Semiha Aksoy
Özen, Deniz Kaptan
Halhallı, Hüseyin Cahit
author_sort Günay, Serkan
collection PubMed
description OBJECTIVE: Pulmonary thromboembolism is a disease with high morbidity and mortality. Various changes occur on the electrocardiogram secondary to pulmonary thromboembolism. The objective of this study was to investigate variations in QT dispersion, Tpeak-Tend duration, and Tpeak-Tend/QT ratio in relation to pulmonary thromboembolism localization and their impacts on 30-day mortality. METHODS: This study was carried out in a tertiary emergency medicine clinic between December 1, 2019 and November 30, 2020. We evaluated correlations between radiological outcomes of patients, QT dispersions, T-wave dispersions, Tpeak-Tend durations, and Tpeak-Tend/QT ratios. We sought statistically significant disparities between these values, considering the presence or localization of pulmonary thromboembolism. The 30-day mortality in pulmonary thromboembolism-diagnosed patients was reassessed. RESULTS: Electrocardiogramfindings revealed that T-wave dispersion (p<0.001), Tpeak-Tend duration (p=0.034), and Tpeak-Tend/corrected QT ratio (p=0.003) were lower in patients than controls. Conversely, QT dispersion (p=0.005) and corrected QT dispersion (p<0.001) were higher in patients. CONCLUSION: Electrocardiogram findings such as T-wave dispersion, QT duration, Tpeak-Tend time, and Tpeak-Tend/corrected QT ratio can detect pulmonary thromboembolism. More studies with larger cohorts are required to further understand the role of QT and corrected QT dispersion in pulmonary thromboembolism patient mortality.
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spelling pubmed-106451812023-11-13 Effect of pulmonary embolism location on electrocardiological parameters Günay, Serkan Şancı, Emre Sarı, Ahmet Emir Gümüş, Semiha Aksoy Özen, Deniz Kaptan Halhallı, Hüseyin Cahit Rev Assoc Med Bras (1992) Original Article OBJECTIVE: Pulmonary thromboembolism is a disease with high morbidity and mortality. Various changes occur on the electrocardiogram secondary to pulmonary thromboembolism. The objective of this study was to investigate variations in QT dispersion, Tpeak-Tend duration, and Tpeak-Tend/QT ratio in relation to pulmonary thromboembolism localization and their impacts on 30-day mortality. METHODS: This study was carried out in a tertiary emergency medicine clinic between December 1, 2019 and November 30, 2020. We evaluated correlations between radiological outcomes of patients, QT dispersions, T-wave dispersions, Tpeak-Tend durations, and Tpeak-Tend/QT ratios. We sought statistically significant disparities between these values, considering the presence or localization of pulmonary thromboembolism. The 30-day mortality in pulmonary thromboembolism-diagnosed patients was reassessed. RESULTS: Electrocardiogramfindings revealed that T-wave dispersion (p<0.001), Tpeak-Tend duration (p=0.034), and Tpeak-Tend/corrected QT ratio (p=0.003) were lower in patients than controls. Conversely, QT dispersion (p=0.005) and corrected QT dispersion (p<0.001) were higher in patients. CONCLUSION: Electrocardiogram findings such as T-wave dispersion, QT duration, Tpeak-Tend time, and Tpeak-Tend/corrected QT ratio can detect pulmonary thromboembolism. More studies with larger cohorts are required to further understand the role of QT and corrected QT dispersion in pulmonary thromboembolism patient mortality. Associação Médica Brasileira 2023-11-13 /pmc/articles/PMC10645181/ /pubmed/37971127 http://dx.doi.org/10.1590/1806-9282.20230733 Text en https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Günay, Serkan
Şancı, Emre
Sarı, Ahmet Emir
Gümüş, Semiha Aksoy
Özen, Deniz Kaptan
Halhallı, Hüseyin Cahit
Effect of pulmonary embolism location on electrocardiological parameters
title Effect of pulmonary embolism location on electrocardiological parameters
title_full Effect of pulmonary embolism location on electrocardiological parameters
title_fullStr Effect of pulmonary embolism location on electrocardiological parameters
title_full_unstemmed Effect of pulmonary embolism location on electrocardiological parameters
title_short Effect of pulmonary embolism location on electrocardiological parameters
title_sort effect of pulmonary embolism location on electrocardiological parameters
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645181/
https://www.ncbi.nlm.nih.gov/pubmed/37971127
http://dx.doi.org/10.1590/1806-9282.20230733
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