Cargando…

Evaluating adherence to government recommendations for post-exposure rabies vaccine among animal-bite victims: A hospital-based study in Bangladesh

Rabies is a fatal but preventable zoonotic disease with an approximately 100% case fatality rate. The most common way to contract rabies is through the bite of a rabid animal. Post-exposure prophylaxis (PEP) by vaccination and/or immunoglobulin therapy is the most effective measure for rabies preven...

Descripción completa

Detalles Bibliográficos
Autores principales: Tamanna, Sadia, Yasmin, Dilruba, Ghosh, Sumon, Dey, Amit Kumar, Das, Tushar Kumar, Chowdhury, Sukanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645289/
https://www.ncbi.nlm.nih.gov/pubmed/37963109
http://dx.doi.org/10.1371/journal.pgph.0002506
_version_ 1785147355447689216
author Tamanna, Sadia
Yasmin, Dilruba
Ghosh, Sumon
Dey, Amit Kumar
Das, Tushar Kumar
Chowdhury, Sukanta
author_facet Tamanna, Sadia
Yasmin, Dilruba
Ghosh, Sumon
Dey, Amit Kumar
Das, Tushar Kumar
Chowdhury, Sukanta
author_sort Tamanna, Sadia
collection PubMed
description Rabies is a fatal but preventable zoonotic disease with an approximately 100% case fatality rate. The most common way to contract rabies is through the bite of a rabid animal. Post-exposure prophylaxis (PEP) by vaccination and/or immunoglobulin therapy is the most effective measure for rabies prevention. The effectiveness of vaccination depends on the level of completion of vaccination. In Bangladesh, no previous studies were conducted to evaluate adherence to government recommendations for post-exposure rabies vaccine among animal-bite cases. We conducted a cross-sectional study to collect information about adherence to government recommendations for post-exposure rabies vaccine. A total of 457 animal bite victims were selected to collect data and follow up after one month of enrollment. The majority of participants (58%, n = 265, 95% CI: 53–63%) had a history of animal bites. Most of the participants (77%) were advised to receive three doses of vaccine and 100% of them completed 3—dose of vaccine. Among the 4—dose recommended group of participants (n = 105), 78% completed full vaccination. Of the 457 participants, 20% received post-exposure vaccine on the day of bite/scratch and the majority of the participants (66%, n = 303, 95% CI: 62–71%) received post-exposure vaccine on the day between the first and third day of bite or scratch. Increasing awareness of the importance of timely vaccination is the key to reducing the time gap between animal bites and intake of the first dose post-exposure vaccine.
format Online
Article
Text
id pubmed-10645289
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-106452892023-11-14 Evaluating adherence to government recommendations for post-exposure rabies vaccine among animal-bite victims: A hospital-based study in Bangladesh Tamanna, Sadia Yasmin, Dilruba Ghosh, Sumon Dey, Amit Kumar Das, Tushar Kumar Chowdhury, Sukanta PLOS Glob Public Health Research Article Rabies is a fatal but preventable zoonotic disease with an approximately 100% case fatality rate. The most common way to contract rabies is through the bite of a rabid animal. Post-exposure prophylaxis (PEP) by vaccination and/or immunoglobulin therapy is the most effective measure for rabies prevention. The effectiveness of vaccination depends on the level of completion of vaccination. In Bangladesh, no previous studies were conducted to evaluate adherence to government recommendations for post-exposure rabies vaccine among animal-bite cases. We conducted a cross-sectional study to collect information about adherence to government recommendations for post-exposure rabies vaccine. A total of 457 animal bite victims were selected to collect data and follow up after one month of enrollment. The majority of participants (58%, n = 265, 95% CI: 53–63%) had a history of animal bites. Most of the participants (77%) were advised to receive three doses of vaccine and 100% of them completed 3—dose of vaccine. Among the 4—dose recommended group of participants (n = 105), 78% completed full vaccination. Of the 457 participants, 20% received post-exposure vaccine on the day of bite/scratch and the majority of the participants (66%, n = 303, 95% CI: 62–71%) received post-exposure vaccine on the day between the first and third day of bite or scratch. Increasing awareness of the importance of timely vaccination is the key to reducing the time gap between animal bites and intake of the first dose post-exposure vaccine. Public Library of Science 2023-11-14 /pmc/articles/PMC10645289/ /pubmed/37963109 http://dx.doi.org/10.1371/journal.pgph.0002506 Text en © 2023 Tamanna et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Tamanna, Sadia
Yasmin, Dilruba
Ghosh, Sumon
Dey, Amit Kumar
Das, Tushar Kumar
Chowdhury, Sukanta
Evaluating adherence to government recommendations for post-exposure rabies vaccine among animal-bite victims: A hospital-based study in Bangladesh
title Evaluating adherence to government recommendations for post-exposure rabies vaccine among animal-bite victims: A hospital-based study in Bangladesh
title_full Evaluating adherence to government recommendations for post-exposure rabies vaccine among animal-bite victims: A hospital-based study in Bangladesh
title_fullStr Evaluating adherence to government recommendations for post-exposure rabies vaccine among animal-bite victims: A hospital-based study in Bangladesh
title_full_unstemmed Evaluating adherence to government recommendations for post-exposure rabies vaccine among animal-bite victims: A hospital-based study in Bangladesh
title_short Evaluating adherence to government recommendations for post-exposure rabies vaccine among animal-bite victims: A hospital-based study in Bangladesh
title_sort evaluating adherence to government recommendations for post-exposure rabies vaccine among animal-bite victims: a hospital-based study in bangladesh
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645289/
https://www.ncbi.nlm.nih.gov/pubmed/37963109
http://dx.doi.org/10.1371/journal.pgph.0002506
work_keys_str_mv AT tamannasadia evaluatingadherencetogovernmentrecommendationsforpostexposurerabiesvaccineamonganimalbitevictimsahospitalbasedstudyinbangladesh
AT yasmindilruba evaluatingadherencetogovernmentrecommendationsforpostexposurerabiesvaccineamonganimalbitevictimsahospitalbasedstudyinbangladesh
AT ghoshsumon evaluatingadherencetogovernmentrecommendationsforpostexposurerabiesvaccineamonganimalbitevictimsahospitalbasedstudyinbangladesh
AT deyamitkumar evaluatingadherencetogovernmentrecommendationsforpostexposurerabiesvaccineamonganimalbitevictimsahospitalbasedstudyinbangladesh
AT dastusharkumar evaluatingadherencetogovernmentrecommendationsforpostexposurerabiesvaccineamonganimalbitevictimsahospitalbasedstudyinbangladesh
AT chowdhurysukanta evaluatingadherencetogovernmentrecommendationsforpostexposurerabiesvaccineamonganimalbitevictimsahospitalbasedstudyinbangladesh