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Type I interferon signature and cycling lymphocytes in macrophage activation syndrome

BACKGROUND: Macrophage activation syndrome (MAS) is a life-threatening complication of Still’s disease (SD) characterized by overt immune cell activation and cytokine storm. We aimed to further understand the immunologic landscape of SD and MAS. METHOD: We profiled PBMCs from people in a healthy con...

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Detalles Bibliográficos
Autores principales: Huang, Zhengping, Brodeur, Kailey E., Chen, Liang, Du, Wobma, Holly, Hsu, Evan E., Liu, Meng, Chang, Joyce C., Chang, Margaret H., Chou, Janet, Day-Lewis, Megan, Dedeoglu, Fatma, Halyabar, Olha, Lederer, James A., Li, Tianwang, Lo, Mindy S., Lu, Meiping, Meidan, Esra, Newburger, Jane W., Randolph, Adrienne G., Son, Mary Beth, Sundel, Robert P., Taylor, Maria L., Wu, Huaxiang, Zhou, Qing, Canna, Scott W., Wei, Kevin, Henderson, Lauren A., Nigrovic, Peter A., Lee, Pui Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645381/
https://www.ncbi.nlm.nih.gov/pubmed/37751296
http://dx.doi.org/10.1172/JCI165616

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