Tretinoin Enhances the Effects of Chemotherapy in Juvenile Myelomonocytic Leukemia Using an Ex Vivo Drug Sensitivity Assay

PURPOSE: Juvenile myelomonocytic leukemia (JMML) is an aggressive pediatric malignancy with myelodysplastic and myeloproliferative features. Curative treatment is restricted to hematopoietic stem-cell transplantation. Fludarabine combined with cytarabine (FLA) and 5-azacitidine (AZA) monotherapy are...

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Detalles Bibliográficos
Autores principales: Stieglitz, Elliot, Gu, Christine J., Richardson, Michelle, Kita, Ryosuke, Santaguida, Marianne T., Ali, Kamran A., Strachan, Debbie C., Dhar, Anukriti, Yam, George, Anderson, Wade, Anderson, Erica, Hübner, Juwita, Tasian, Sarah K., Loh, Mignon L., Lacher, Markus D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2023
Materias:
ORIGINAL REPORTS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645413/
https://www.ncbi.nlm.nih.gov/pubmed/37944074
http://dx.doi.org/10.1200/PO.23.00302

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