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Mechanism of substrate binding and transport in BASS transporters

The bile acid sodium symporter (BASS) family transports a wide array of molecules across membranes, including bile acids in humans, and small metabolites in plants. These transporters, many of which are sodium-coupled, have been shown to use an elevator mechanism of transport, but exactly how substr...

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Detalles Bibliográficos
Autores principales: Becker, Patrick, Naughton, Fiona, Brotherton, Deborah, Pacheco-Gomez, Raul, Beckstein, Oliver, Cameron, Alexander D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645422/
https://www.ncbi.nlm.nih.gov/pubmed/37963091
http://dx.doi.org/10.7554/eLife.89167