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Plain radiographic indices are reliable indicators for quantitative bone mineral density in male and female patients before total hip arthroplasty

Osteoporosis is underdiagnosed in patients undergoing total hip arthroplasty (THA). Bone mineral density measurement by dual-energy X-ray absorptiometry (DXA) is the gold standard, but indices on plain hip radiographs also seemed to be reliable screening tools in female or Asian ethnicities in previ...

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Autores principales: Rohe, Sebastian, Böhle, Sabrina, Matziolis, Georg, Jacob, Benjamin, Brodt, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645725/
https://www.ncbi.nlm.nih.gov/pubmed/37963967
http://dx.doi.org/10.1038/s41598-023-47247-w
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author Rohe, Sebastian
Böhle, Sabrina
Matziolis, Georg
Jacob, Benjamin
Brodt, Steffen
author_facet Rohe, Sebastian
Böhle, Sabrina
Matziolis, Georg
Jacob, Benjamin
Brodt, Steffen
author_sort Rohe, Sebastian
collection PubMed
description Osteoporosis is underdiagnosed in patients undergoing total hip arthroplasty (THA). Bone mineral density measurement by dual-energy X-ray absorptiometry (DXA) is the gold standard, but indices on plain hip radiographs also seemed to be reliable screening tools in female or Asian ethnicities in previous studies. Given the lack of knowledge about male patients and Caucasian ethnicities, this study was conducted to evaluate plane hip radiographic indices as a screening tool for osteopenia and osteoporosis in Caucasian female and also male patients before undergoing THA. A retrospective analysis of 216 elderly patients with pre-existing DXA before hip arthroplasty was performed and four indices were calculated on plain hip radiographs: Canal-Flare-Index (CFI), Canal-Calcar-Ratio (CCR), Canal-Bone-Ratio (CBR) 7 and 10 cm below the lesser trochanter. They were correlated with femoral neck DXA T-scores by Pearson’s correlation and intraclass correlation coefficient, and a ROC analysis was performed. A total of 216 patients (49.5% male) were included. CBR-7 and -10 were highly correlated (p < 0.001) with femoral neck T-score in males (Pearson’s correlation CBR-7 r = − 0.60, CBR-10 r = − 0.55) and females (r = − 0.74, r = − 0.77). CBR-7 and -10 also showed good diagnostic accuracy for osteoporosis in the ROC analysis in males (CBR-7: AUC = 0.75, threshold = 0.51; CBR-10: 0.63; 0.50) and females (CBR-7: AUC = 0.87, threshold = 0.55; CBR-10: 0.90; 0.54). Indices such as the Canal Bone Ratio (CBR) 7 or 10 cm below the lesser trochanter on plain hip radiographs are a good screening tool for osteopenia and osteoporosis on plain hip radiographs and can be used to initiate further diagnostics like the gold standard DXA. They differ between male and female patients.
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spelling pubmed-106457252023-11-14 Plain radiographic indices are reliable indicators for quantitative bone mineral density in male and female patients before total hip arthroplasty Rohe, Sebastian Böhle, Sabrina Matziolis, Georg Jacob, Benjamin Brodt, Steffen Sci Rep Article Osteoporosis is underdiagnosed in patients undergoing total hip arthroplasty (THA). Bone mineral density measurement by dual-energy X-ray absorptiometry (DXA) is the gold standard, but indices on plain hip radiographs also seemed to be reliable screening tools in female or Asian ethnicities in previous studies. Given the lack of knowledge about male patients and Caucasian ethnicities, this study was conducted to evaluate plane hip radiographic indices as a screening tool for osteopenia and osteoporosis in Caucasian female and also male patients before undergoing THA. A retrospective analysis of 216 elderly patients with pre-existing DXA before hip arthroplasty was performed and four indices were calculated on plain hip radiographs: Canal-Flare-Index (CFI), Canal-Calcar-Ratio (CCR), Canal-Bone-Ratio (CBR) 7 and 10 cm below the lesser trochanter. They were correlated with femoral neck DXA T-scores by Pearson’s correlation and intraclass correlation coefficient, and a ROC analysis was performed. A total of 216 patients (49.5% male) were included. CBR-7 and -10 were highly correlated (p < 0.001) with femoral neck T-score in males (Pearson’s correlation CBR-7 r = − 0.60, CBR-10 r = − 0.55) and females (r = − 0.74, r = − 0.77). CBR-7 and -10 also showed good diagnostic accuracy for osteoporosis in the ROC analysis in males (CBR-7: AUC = 0.75, threshold = 0.51; CBR-10: 0.63; 0.50) and females (CBR-7: AUC = 0.87, threshold = 0.55; CBR-10: 0.90; 0.54). Indices such as the Canal Bone Ratio (CBR) 7 or 10 cm below the lesser trochanter on plain hip radiographs are a good screening tool for osteopenia and osteoporosis on plain hip radiographs and can be used to initiate further diagnostics like the gold standard DXA. They differ between male and female patients. Nature Publishing Group UK 2023-11-14 /pmc/articles/PMC10645725/ /pubmed/37963967 http://dx.doi.org/10.1038/s41598-023-47247-w Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Rohe, Sebastian
Böhle, Sabrina
Matziolis, Georg
Jacob, Benjamin
Brodt, Steffen
Plain radiographic indices are reliable indicators for quantitative bone mineral density in male and female patients before total hip arthroplasty
title Plain radiographic indices are reliable indicators for quantitative bone mineral density in male and female patients before total hip arthroplasty
title_full Plain radiographic indices are reliable indicators for quantitative bone mineral density in male and female patients before total hip arthroplasty
title_fullStr Plain radiographic indices are reliable indicators for quantitative bone mineral density in male and female patients before total hip arthroplasty
title_full_unstemmed Plain radiographic indices are reliable indicators for quantitative bone mineral density in male and female patients before total hip arthroplasty
title_short Plain radiographic indices are reliable indicators for quantitative bone mineral density in male and female patients before total hip arthroplasty
title_sort plain radiographic indices are reliable indicators for quantitative bone mineral density in male and female patients before total hip arthroplasty
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645725/
https://www.ncbi.nlm.nih.gov/pubmed/37963967
http://dx.doi.org/10.1038/s41598-023-47247-w
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