The formation of K(V)2.1 macro-clusters is required for sex-specific differences in L-type Ca(V)1.2 clustering and function in arterial myocytes

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In arterial myocytes, the canonical function of voltage-gated Ca(V)1.2 and K(V)2.1 channels is to induce myocyte contraction and relaxation through their responses to membrane depolarization, respectively. Paradoxically, K(V)2.1 also plays a sex-specific role by promoting the clustering and activity...

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Detalles Bibliográficos
Autores principales: Matsumoto, Collin, O’Dwyer, Samantha C., Manning, Declan, Hernandez-Hernandez, Gonzalo, Rhana, Paula, Fong, Zhihui, Sato, Daisuke, Clancy, Colleen E., Vierra, Nicholas C., Trimmer, James S., Fernando Santana, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645748/
https://www.ncbi.nlm.nih.gov/pubmed/37963972
http://dx.doi.org/10.1038/s42003-023-05527-1

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