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Spatial–temporal analysis and spatial drivers of hepatitis-related deaths in 183 countries, 2000–2019

Hepatitis is the seventh leading cause of mortality worldwide and is the only communicable disease where mortality is increasing, yet the long-term spatial–temporal variation at global scale and its possible causes, i.e., drivers, remain unknown. Firstly, this study employed the measure of spatial a...

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Autores principales: Li, Jie, Xu, Zejia, Zhu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645816/
https://www.ncbi.nlm.nih.gov/pubmed/37963888
http://dx.doi.org/10.1038/s41598-023-45672-5
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author Li, Jie
Xu, Zejia
Zhu, Hong
author_facet Li, Jie
Xu, Zejia
Zhu, Hong
author_sort Li, Jie
collection PubMed
description Hepatitis is the seventh leading cause of mortality worldwide and is the only communicable disease where mortality is increasing, yet the long-term spatial–temporal variation at global scale and its possible causes, i.e., drivers, remain unknown. Firstly, this study employed the measure of spatial autocorrelation, Moran’s I, and the measure of local spatial cluster, Getis-Ord G(i)*, to characterize the spatial variation of mortality due to hepatitis in 183 countries globally for years 2000, 2010, 2015 and 2019. Then, a novel spatial statistical method, named the Geographical Detector, was utilized to investigate eight possible influencing factors, i.e., risk factors, of the spatial–temporal variation of mortality due to hepatitis. The results showed significant disparities of hepatitis-related mortality rates among countries. Hot spots, representing locations with higher mortality rates, were consistently observed in Africa, East Asia, and Southeast Asia, while the cold spots, representing locations with lower mortality rates, were predominantly found in Europe and the Americas. Potential spatial drivers of hepatitis mortality, identified by geographical detector, include “health expenditure”, “universal health coverage”, and “per capita income”. However, “hepatitis B immunization” and “total population” were not identified as significant spatial drivers for hepatitis mortality The findings highlighted the critical role of socioeconomic factors in the variations in hepatitis mortality, and pointed out relative importance of increasing health expenditure, per capita income, and improve universal health coverage on alleviating global hepatitis-related mortality.
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spelling pubmed-106458162023-11-13 Spatial–temporal analysis and spatial drivers of hepatitis-related deaths in 183 countries, 2000–2019 Li, Jie Xu, Zejia Zhu, Hong Sci Rep Article Hepatitis is the seventh leading cause of mortality worldwide and is the only communicable disease where mortality is increasing, yet the long-term spatial–temporal variation at global scale and its possible causes, i.e., drivers, remain unknown. Firstly, this study employed the measure of spatial autocorrelation, Moran’s I, and the measure of local spatial cluster, Getis-Ord G(i)*, to characterize the spatial variation of mortality due to hepatitis in 183 countries globally for years 2000, 2010, 2015 and 2019. Then, a novel spatial statistical method, named the Geographical Detector, was utilized to investigate eight possible influencing factors, i.e., risk factors, of the spatial–temporal variation of mortality due to hepatitis. The results showed significant disparities of hepatitis-related mortality rates among countries. Hot spots, representing locations with higher mortality rates, were consistently observed in Africa, East Asia, and Southeast Asia, while the cold spots, representing locations with lower mortality rates, were predominantly found in Europe and the Americas. Potential spatial drivers of hepatitis mortality, identified by geographical detector, include “health expenditure”, “universal health coverage”, and “per capita income”. However, “hepatitis B immunization” and “total population” were not identified as significant spatial drivers for hepatitis mortality The findings highlighted the critical role of socioeconomic factors in the variations in hepatitis mortality, and pointed out relative importance of increasing health expenditure, per capita income, and improve universal health coverage on alleviating global hepatitis-related mortality. Nature Publishing Group UK 2023-11-13 /pmc/articles/PMC10645816/ /pubmed/37963888 http://dx.doi.org/10.1038/s41598-023-45672-5 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Li, Jie
Xu, Zejia
Zhu, Hong
Spatial–temporal analysis and spatial drivers of hepatitis-related deaths in 183 countries, 2000–2019
title Spatial–temporal analysis and spatial drivers of hepatitis-related deaths in 183 countries, 2000–2019
title_full Spatial–temporal analysis and spatial drivers of hepatitis-related deaths in 183 countries, 2000–2019
title_fullStr Spatial–temporal analysis and spatial drivers of hepatitis-related deaths in 183 countries, 2000–2019
title_full_unstemmed Spatial–temporal analysis and spatial drivers of hepatitis-related deaths in 183 countries, 2000–2019
title_short Spatial–temporal analysis and spatial drivers of hepatitis-related deaths in 183 countries, 2000–2019
title_sort spatial–temporal analysis and spatial drivers of hepatitis-related deaths in 183 countries, 2000–2019
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645816/
https://www.ncbi.nlm.nih.gov/pubmed/37963888
http://dx.doi.org/10.1038/s41598-023-45672-5
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