Characterization of NFE2L1-616, an isoform of nuclear factor-erythroid-2 related transcription factor-1 that activates antioxidant response element-regulated genes

The NFE2L1 transcription factor (aka Nrf1) is a basic leucine zipper protein that performs a critical role in the cellular stress response pathway. Here, we characterized a novel variant of NFE2L1 referred to as NFE2L1-616. The transcript encoding NFE2L1-616 is derived from an intronic promoter, and...

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Detalles Bibliográficos
Autores principales: Ho, Daniel V., Suryajaya, Kaylen G., Manh, Kaitlyn, Duong, Amanda N., Chan, Jefferson Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646089/
https://www.ncbi.nlm.nih.gov/pubmed/37963997
http://dx.doi.org/10.1038/s41598-023-47055-2

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