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Current and future research on the association between gut microbiota and breast cancer

Breast cancer (BC) is a prevalent malignancy. There exists a strong association between gut microbiota (GM) and the development of BC. The GM composition in individuals with BC significantly differs from that in their healthy counterparts. Furthermore, the distribution of GM varies significantly amo...

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Detalles Bibliográficos
Autores principales: Liu, Kuan, Jia, Nan, Shi, Hongyun, Ran, Yuge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646191/
https://www.ncbi.nlm.nih.gov/pubmed/38029117
http://dx.doi.org/10.3389/fmicb.2023.1272275
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author Liu, Kuan
Jia, Nan
Shi, Hongyun
Ran, Yuge
author_facet Liu, Kuan
Jia, Nan
Shi, Hongyun
Ran, Yuge
author_sort Liu, Kuan
collection PubMed
description Breast cancer (BC) is a prevalent malignancy. There exists a strong association between gut microbiota (GM) and the development of BC. The GM composition in individuals with BC significantly differs from that in their healthy counterparts. Furthermore, the distribution of GM varies significantly among individuals with different types of BC. The GM can impact BC through metabolite secretion, the gut-mammary axis, and other pathways. Modulating the GM can serve as a very promising potential therapeutic strategy in the treatment of BC. This article will summarize existing research, focusing on the relationship between intestinal microbiota and BC. At the same time, the project will also analyze the application value of intestinal microorganisms in BC intervention work, so as to provide a reference for the further development of BC prevention and treatment work.
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spelling pubmed-106461912023-10-30 Current and future research on the association between gut microbiota and breast cancer Liu, Kuan Jia, Nan Shi, Hongyun Ran, Yuge Front Microbiol Microbiology Breast cancer (BC) is a prevalent malignancy. There exists a strong association between gut microbiota (GM) and the development of BC. The GM composition in individuals with BC significantly differs from that in their healthy counterparts. Furthermore, the distribution of GM varies significantly among individuals with different types of BC. The GM can impact BC through metabolite secretion, the gut-mammary axis, and other pathways. Modulating the GM can serve as a very promising potential therapeutic strategy in the treatment of BC. This article will summarize existing research, focusing on the relationship between intestinal microbiota and BC. At the same time, the project will also analyze the application value of intestinal microorganisms in BC intervention work, so as to provide a reference for the further development of BC prevention and treatment work. Frontiers Media S.A. 2023-10-30 /pmc/articles/PMC10646191/ /pubmed/38029117 http://dx.doi.org/10.3389/fmicb.2023.1272275 Text en Copyright © 2023 Liu, Jia, Shi and Ran. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
Liu, Kuan
Jia, Nan
Shi, Hongyun
Ran, Yuge
Current and future research on the association between gut microbiota and breast cancer
title Current and future research on the association between gut microbiota and breast cancer
title_full Current and future research on the association between gut microbiota and breast cancer
title_fullStr Current and future research on the association between gut microbiota and breast cancer
title_full_unstemmed Current and future research on the association between gut microbiota and breast cancer
title_short Current and future research on the association between gut microbiota and breast cancer
title_sort current and future research on the association between gut microbiota and breast cancer
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646191/
https://www.ncbi.nlm.nih.gov/pubmed/38029117
http://dx.doi.org/10.3389/fmicb.2023.1272275
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