Cyclic Stretch Promotes Cellular Reprogramming Process through Cytoskeletal‐Nuclear Mechano‐Coupling and Epigenetic Modification (Adv. Sci. 32/2023)

Cell Reprogramming In article number 2303395, Jung‐Hwan Lee, Hosup Shim, Hae‐Won Kim, co‐workers revealed that cyclic stretching of cells during reprogramming process significantly enhanced the efficiency of iPSC production through mechanotransduction molecules along the cytoskeletal‐nuclear axis by...

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Detalles Bibliográficos
Autores principales: Park, Sung‐Min, Lee, Jung‐Hwan, Ahn, Kwang Sung, Shim, Hye Won, Yoon, Ji‐Young, Hyun, Jeongeun, Lee, Jun Hee, Jang, Sunyoung, Yoo, Kyung Hyun, Jang, Yoon‐Kwan, Kim, Tae‐Jin, Kim, Hyun Kyu, Lee, Man Ryul, Jang, Jun‐Hyeog, Shim, Hosup, Kim, Hae‐Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646215/
http://dx.doi.org/10.1002/advs.202370218
Descripción
Sumario:Cell Reprogramming In article number 2303395, Jung‐Hwan Lee, Hosup Shim, Hae‐Won Kim, co‐workers revealed that cyclic stretching of cells during reprogramming process significantly enhanced the efficiency of iPSC production through mechanotransduction molecules along the cytoskeletal‐nuclear axis by epigenetic changes. This mechanical cell‐engineering aids in mass‐production of iPSCs and regenerative medicine. [Image: see text]

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