The Critical Role of The Piezo1/β‐catenin/ATF4 Axis on The Stemness of Gli1(+) BMSCs During Simulated Microgravity‐Induced Bone Loss

Disuse osteoporosis is characterized by decreased bone mass caused by abnormal mechanical stimulation of bone. Piezo1 is a major mechanosensitive ion channel in bone homeostasis. However, whether intervening in the action of Piezo1 can rescue disuse osteoporosis remains unresolved. In this study, a...

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Detalles Bibliográficos
Autores principales: Hu, Yuxiang, Tian, Hongtao, Chen, Wei, Liu, Yunlu, Cao, Yulin, Pei, Hongxin, Ming, Chaochang, Shan, Cunqing, Chen, Xihui, Dai, Zhipeng, Yang, Shuhua, Shao, Zengwu, Lan, Shenghui, Liu, Yong, Tong, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646271/
https://www.ncbi.nlm.nih.gov/pubmed/37759400
http://dx.doi.org/10.1002/advs.202303375

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