Cargando…

Promising derivatives of rutaecarpine with diverse pharmacological activities

Rutaecarpine (RUT) is a natural pentacyclic indolopyridoquinazolinone alkaloid first isolated from one of the most famous traditional Chinese herbs, Evodia rutaecarpa, which is used for treating a variety of ailments, including headaches, gastrointestinal disorders, postpartum hemorrhage, amenorrhea...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Deping, Huang, Ziqian, Xu, Xiaojun, Li, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646507/ https://www.ncbi.nlm.nih.gov/pubmed/38025082 http://dx.doi.org/10.3389/fchem.2023.1199799

Ejemplares similares

Pharmacological Effects of Rutaecarpine as a Cardiovascular Protective Agent
por: Jia, Sujie, et al.
Publicado: (2010)

Electrosynthesis of polycyclic quinazolinones and rutaecarpine from isatoic anhydrides and cyclic amines
por: Chen, Xingyu, et al.
Publicado: (2020)

Progress in the Studies on Rutaecarpine
por: Lee, Seung Ho, et al.
Publicado: (2008)

Neuroprotective effects of rutaecarpine on cerebral ischemia reperfusion injury
por: Yan, Chunlin, et al.
Publicado: (2013)

Time effect of rutaecarpine on caffeine pharmacokinetics in rats
por: Estari, Rohit Kumar, et al.
Publicado: (2021)

(±)-Evodiakine, A Pair of Rearranged Rutaecarpine-Type Alkaloids From Evodia rutaecarpa
por: Li, Yan-Hong, et al.
Publicado: (2016)

Progress in Studies on Rutaecarpine. II.—Synthesis and Structure-Biological Activity Relationships
por: Son, Jong-Keun, et al.
Publicado: (2015)

Enhanced transdermal delivery of evodiamine and rutaecarpine using microemulsion
por: Zhang, Yong-Tai, et al.
Publicado: (2011)

Effects of Oral Rutaecarpine on the Pharmacokinetics of Intravenous Chlorzoxazone in Rats
por: Bista, Sudeep R., et al.
Publicado: (2008)

In vitro cellular uptake of evodiamine and rutaecarpine using a microemulsion
por: Zhang, Yong-Tai, et al.
Publicado: (2012)

Rutaecarpine Inhibits Doxorubicin-Induced Oxidative Stress and Apoptosis by Activating AKT Signaling Pathway
por: Liao, Zi-Qi, et al.
Publicado: (2022)

Rutaecarpine Ameliorates Pressure Overload Cardiac Hypertrophy by Suppression of Calcineurin and Angiotensin II
por: Li, Shujun, et al.
Publicado: (2021)

Anthocyanins: Promising Natural Products with Diverse Pharmacological Activities
por: Liu, Jiaqi, et al.
Publicado: (2021)

Antiproliferative Activity and Cellular Uptake of Evodiamine and Rutaecarpine Based on 3D Tumor Models
por: Guo, Hui, et al.
Publicado: (2016)

Evodiamine and Rutaecarpine as Potential Anticancer Compounds: A Combined Computational Study
por: Liu, Jingli, et al.
Publicado: (2022)

Rutaecarpine Inhibits U87 Glioblastoma Cell Migration by Activating the Aryl Hydrocarbon Receptor Signaling Pathway
por: Liu, Yiyun, et al.
Publicado: (2021)

Rutaecarpine targets hERG channels and participates in regulating electrophysiological properties leading to ventricular arrhythmia
por: Zhan, Ge, et al.
Publicado: (2021)

Rutaecarpine prevents hypertensive cardiac hypertrophy involving the inhibition of Nox4‐ROS‐ADAM17 pathway
por: Zeng, Si‐yu, et al.
Publicado: (2018)

Involvement of TRPV1 in the expression and release of calcitonin gene-related peptide induced by rutaecarpine
por: Yang, Yongmei, et al.
Publicado: (2018)

Fluorine-Modified Rutaecarpine Exerts Cyclooxygenase-2 Inhibition and Anti-inflammatory Effects in Lungs
por: Lee, Chiming, et al.
Publicado: (2019)

Rutaecarpine Protects against Acetaminophen-Induced Acute Liver Injury in Mice by Activating Antioxidant Enzymes
por: Choi, Jae Ho, et al.
Publicado: (2021)

Rutaecarpine suppresses the proliferation and metastasis of colon cancer cells by regulating the STAT3 signaling
por: Chan, Shixin, et al.
Publicado: (2022)

Berberine nanoparticles for promising sonodynamic therapy of a HeLa xenograft tumour
por: Liu, Hanqing, et al.
Publicado: (2019)

Lonicera japonica Thunb. as a promising antibacterial agent for Bacillus cereus ATCC14579 based on network pharmacology, metabolomics, and in vitro experiments
por: Xu, Nan, et al.
Publicado: (2023)

Promising activated carbon derived from sugarcane tip as electrode material for high-performance supercapacitors
por: Wei, Bo, et al.
Publicado: (2021)

Rutaecarpine induces the differentiation of triple-negative breast cancer cells through inhibiting fumarate hydratase
por: Lei, Jie, et al.
Publicado: (2023)

Comprehensive review of α-carboline alkaloids: Natural products, updated synthesis, and biological activities
por: Li, Deping, et al.
Publicado: (2022)

3-Hydroxyflavone derivatives: promising scaffolds for fluorescent imaging in cells
por: Zhao, Xueke, et al.
Publicado: (2021)

Network pharmacology combined with functional metabolomics discover bile acid metabolism as a promising target for mirabilite against colorectal cancer
por: Sun, Hui, et al.
Publicado: (2018)

Fucoxanthin: A Promising Phytochemical on Diverse Pharmacological Targets
por: Mumu, Mumtaza, et al.
Publicado: (2022)

5-Fluorouracil Combined with Rutaecarpine Synergistically Suppresses the Growth of Colon Cancer Cells by Inhibiting STAT3
por: Yu, Zhen, et al.
Publicado: (2023)

Rutaecarpine ameliorates osteoarthritis by inhibiting PI3K/AKT/NF-κB and MAPK signalling transduction through integrin αVβ3
por: Wan, Junlai, et al.
Publicado: (2023)

Chemosensing Properties of Coumarin Derivatives: Promising Agents with Diverse Pharmacological Properties, Docking and DFT Investigation
por: Al-Hazmy, Sadeq M., et al.
Publicado: (2022)

Pharmacological and natural products diversity of the brown algae genus Sargassum
por: Rushdi, Mohammed I., et al.
Publicado: (2020)

Rutaecarpine Promotes Adipose Thermogenesis and Protects against HFD-Induced Obesity via AMPK/PGC-1α Pathway
por: Chen, Dandan, et al.
Publicado: (2022)

Research progress on MOFs and their derivatives as promising and efficient electrode materials for electrocatalytic hydrogen production from water
por: Cao, Xuankai, et al.
Publicado: (2023)

Synthesis and pharmacological activities of azo dye derivatives incorporating heterocyclic scaffolds: a review
por: Mezgebe, Kibrom, et al.
Publicado: (2022)

Rutaecarpine Ameliorates Murine N-Methyl-N’-Nitro-N-Nitrosoguanidine-Induced Chronic Atrophic Gastritis by Sonic Hedgehog Pathway
por: He, Yong, et al.
Publicado: (2023)

Rutaecarpine Increases Anticancer Drug Sensitivity in Drug-Resistant Cells through MARCH8-Dependent ABCB1 Degradation
por: Zou, Tingting, et al.
Publicado: (2021)

Structurally diverse diterpenoid alkaloids from the lateral roots of Aconitum carmichaelii Debx. and their anti-tumor activities based on in vitro systematic evaluation and network pharmacology analysis
por: Yu, Yang, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_0l95d4v3gan2iv8dmjhv72lkjd